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林强
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副研究员 硕士生导师
副研究员 硕士生导师
基因组所
★生物信息学  、 农艺与种业
linqiang@caas.cn

个人简介

  1. 2002-09至2006-07, 吉林大学, 生命科学学院, 制药工程专业, 学士
  2. 2006-09至2011-07, 中国科学院北京基因组研究所, 基因组学, 博士
  3. 2010-04至2016-06, 沙特阿卜杜勒阿齐兹国王科技城, 联合基因组研究中心, 研究科学家
  4. 2011-09至2014-01, 中国科学院北京基因组研究所, 中国科学院基因组科学与信息重点实验室, 助理研究员
  5. 2014-01至2019-01, 中国科学院北京基因组研究所, 中国科学院基因组科学与信息重点实验室, 副研究员
  6. 2019-01至现在, 中国农业科学院农业基因组研究所, 组学技术研究中心, 副研究员


研究方向

植物基因组的自动化注释,基因组学应用
项目情况

1. 蓖麻、芝麻、橡胶等作物基因组重测序及组装

2. 昆虫基因组

3. 病原菌核酸提取及耐药性研究


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科研项目

1)建立植物基因组的量化性注释流程,开发组学数据应用的新方法与新技术。

2)深度挖掘油料作物特有经济性状的形成分子机制。参与海南黎族特色植物基因组、橡胶基因组、芝麻基因组、昆虫基因组等合作项目

3)与临床检验科合作应用性panel、流程及检测工具。


研究成果

1.  Jianjun Lu, Cheng Pan, Wei Fan, Wanfei Liu, Huayan Zhao, Donghai Li,Sen Wang, Lianlian Hu, Bing He, Kun Qian, Rui Qin, Jue Ruan, Qiang Lin*, Shiyou Lü*, Peng Cui*. AChromosome-level Assembly of A Wild Castor Genome Provides New Insights intothe Adaptive Evolution in A Tropical Desert, Genomics, Proteomics & Bioinformatics, 2021 Jul30;S1672-0229(21)00162-5

2.  Xing Shi*, Zhancheng Gao*, Qiang Lin, Liping Zhao, Qin Ma, YuKang, Jun Yu. Meta-analysis Reveals Potential Influence of Oxidative Stress onthe Airway Microbiomes of Cystic Fibrosis Patients. Genomics Proteomics &Bioinformatics.2020

3. Xupo Ding*; Wenli Mei*; QiangLin*; Hao Wang; Jun Wang; Shiqing Peng; Huiliang Li; Jiahong Zhu; Wei Li;Pei Wang; Huiqin Chen; Wenhua Dong; Dong Guo; Caihong Cai; Shengzhuo Huang;Peng Cui#; Haofu Dai#; Genome sequence of the agarwood tree Aquilaria sinensis(Lour.) Spreng: the first chromosome-level draft genome in the Thymelaeceaefamily, GigaScience, 2020, 9(13), giaa013

4. Wei Fan, Jianjun Lu, Cheng Pan, Meilian Tan, Qiang Lin, Wanfei Liu, Donghai Li, Lijun Wang, Lianlian Hu, LeiWang, Chen Chen, Aimin Wu, Xinxin Yu, Jue Ruan, Jun Yu, Songnian Hu, XingchuYan, Shiyou Lü & Peng Cui. Sequencing of Chinese castor lines revealsgenetic signatures of selection and yield-associated loci. Nature Communication. 2019.10.3418

5. Muhammad Ramzan Manwar, Changjun Shao, Xing Shi, Jian Wang, Qiang Lin, Yigang Tong, Yu Kang. Thebacterial RNA ligase RtcB accelerates the repair process of fragmented rRNAupon releasing the antibiotic stress. Science China Life Sciences. 2020,64(2):251-258

6.  Wanfei Liu*, Shuangyang Wu*, Qiang Lin*, Shenghan Gao, XiaoweiZhang, Hasan Awad Aljohi, Jun Yu#, Songnian Hu#. RGAAT - Reference based genomeassembly and annotation tool for new genome and known genome upgrade. GenomicsProteomics & Bioinformatics. 2018, 16(5), 373-381

7. Cui Peng*, Qiang Lin*, Fang D*… Songnian Hu#,Shiyou Lv#. Tung tree (Vernicia fordii, Hemsl.) genome and transcriptomesequencing reveals coordinate upregulation of fatty acid beta-oxidation andtriacylglycerol biosynthesis pathways during eleostearic acid accumulation inseeds. Plant and Cell Physiology.2018

8.  Wu Shuangyang , Liu Wanfei , Aljohi Hasan Awad , Alromaih Sarah A. ,Alanazi Ibrahim O. , Lin Qiang# , Yu Jun#, and HuSongnian#. REDO: RNA Editing Detection in Plant Organelles Based on VariantCalling Results. Journal of Computational Biology. 2018. May;25(5)

9.  Zilong He, Chengwei Zhang, Wanfei Liu, Qiang Lin, Ting Wei,Hasan Awad Aljohi, Wei-hua Chen, Songnian Hu. DRDB: An online date palm genomicresource database. Frontiers Plant Science.2017.11

10. Hasan Awad Aljohi*, Wanfei Liu*, Qiang Lin*, Jun Yu# andSongnian Hu#. ISVASE: identification of sequence variant associated withsplicing event using RNA- seq data. BMC Bioinformatics.2017 18:320

11. Hasan Awad Aljohi*, Wanfei Liu*, Qiang Lin*...SongnianHu#, Jun Yu#. Complete Sequence and Comparative Analysis of the MitochondrialGenome of Coconut Palm (Cocos nucifera). PLoS One. 2016.11 (10)

12. Xin Chengqi*, Liu Wanfei*, Lin Qiang*...Yu Jun. ProfilingmicroRNA expression during multi-staged date palm (Phoenix dactylifera L.)fruit development. Genomics. 2015 Apr;105(4):242-51

13. Chaorong Tang, Meng Yang, Yongjun Fang, Yingfeng Luo, ShenghanGao...Qiang Lin... Jun Yu, Songnian Hu, and Huasun Huang. The rubbertree genome reveals new insights into rubber production and species adaptation.NaturePlant. 2016, 2(6)

14. Wei Xu*, Chengqi Xin*, Qiang Lin*, …, Songnian Hu. AdolescentMouse Takes on An Active Transcriptomic Expression During Postnatal CerebralDevelopment. Genomics Proteomics & Bioinformatics 12(2014) 111-119

15. Yadong Yang, …,Qiang Lin, …. Transcriptome Dynamicsduring Human Erythroid Differentiation and Development. Genomics. 10/2013;102(5):231-41.

16. Ibrahim S. Al-Mssallem*, Songnian Hu*, Xiaowei Zhang*, QiangLin*, Wanfei Liu*, Jun Tan*,… , Jun Yu. Genome Sequences and GeneticVariations of Date Palm (Phoenix dactylifera L.). Nature Communication.08/2013; 4:2274

17. Wei Gong, Linlin Pan, Qiang Lin,..., Jun Yu. Transcriptomeprofiling of the developing postnatal mouse testis using next-generationsequencing. Science China Life sciences. 12/2012

18. Guangyu Zhang, …,Qiang Lin, …, Jun Yu. Large-scalecollection and annotation of gene models for date palm (Phoenix dactylifera,L.). Plantmolecular biology. 06/2012; 79(6):521-36

19. Peng Cui, …, Qiang Lin, …, Jun Yu. Theassociation between H3K4me3 and antisense transcription. Genomics, proteomics &bioinformatics. 04/2012; 10(2):74-81.

20. Peng Cui, Wanfei Liu, Yuhui Zhao, Qiang Lin, …, Jun Yu,Songnian Hu. Comparative analyses of H3K4 and H3K27 trimethylations between themouse cerebrum and testis. Genomics, proteomics & bioinformatics.04/2012; 10(2):82-93

21. Qiang Lin*, Peng Cui*, Feng Ding,Songnian Hu, Jun Yu. Replication-Associated Mutational Pressure (RMP) GovernsStrand-Biased Compositional Asymmetry (SCA) and Gene Organization in AnimalMitochondrial Genomes. Current Genomics. 03/2012;13(1):28-36.

22. Peng Cui*, Qiang Lin*, Feng Ding*, Songnian Hu,Jun Yu. The transcript-centric mutations in human genomes. Genomics, proteomics &bioinformatics. 02/2012; 10(1):11-22.

23. Peng Cui*, Feng Ding*, Qiang Lin*, Lingfang Zhang, Ang Li,Zhang Zhang, Songnian Hu, Jun Yu. Distinct contributions of replication andtranscription to mutation rate variation of human genomes. Genomics, proteomics &bioinformatics. 02/2012; 10(1):4-10.

24. Guohua Song, Qiang Lin, Wenbin Yue, Tianfu Liu,Songnian Hu. Sequence analysis of the complete mitochondrial genome andmolecular evolution of Cricetulus griseus. Acta Laboratorium Animalis Scientia Sinica.2012;(1):70~75

25. Huitao Liu, Peng Cui, Kehui Zhan, Qiang Lin, …, Jun Yu,Aimin Zhang. Comparative analysis of mitochondrial genomes between a wheatK-type cytoplasmic male sterility (CMS) line and its maintainer line. BMCgenomics. 03/2011; 12:163

26. Wanfei Liu, Yuhui Zhao, Peng Cui, Qiang Lin, …, Jun Yu,Songnian Hu. Thousands of Novel Transcripts Identified in Mouse Cerebrum,Testis, and ES Cells Based on ribo-minus RNA Sequencing. Frontiers in genetics.01/2011; 2:93.

27. Peng Cui*, Qiang Lin*, …, Jun Yu. Thedisequilibrium of nucleosomes distribution along chromosomes plays a functionaland evolutionarily role in regulating gene expression. PloS One. 01/2011;6(8):e23219

28. Peng Cui*, Qiang Lin*, Feng Ding*, …, Jun Yu. Acomparison between ribo-minus RNA-sequencing and polyA-selected RNA-sequencing.Genomics.11/2010; 96(5):259-65.

29. Peng Cui*, Qiang Lin*, Chengqi Xin*,…, Jun Yu.Hydroxyurea-induced global transcriptional suppression in mouse ES cells. Carcinogenesis.09/2010; 31(9):1661-8.

30. Peng Cui, Huitao Liu, Qiang Lin, …, Jun Yu. A completemitochondrial genome of wheat (Triticumaestivum cv. Chinese Yumai), and fastevolving mitochondrial genes in higher plants. Journal of genetics.12/2009; 88(3):299-307

31. Peng Cui*, Lingfang Zhang*, Qiang Lin*, …, Jun Yu. A novelmechanism of epigenetic regulation: nucleosome-space occupancy. Biochemicaland biophysical research communications. 11/2009; 391(1):884-9


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