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郭惠明,中国农业科学院生物技术研究所副研究员。近年来,主要从事棉花抗逆、抗病基因资源挖掘及其功能分析方面的研究,以及通过农杆菌介导的遗传转化方法创制转基因棉花抗逆新材料。
先后主持转基因专项(2020ZX08009-05B)国家自然科学基金青年基金(31201531)及转基因专项子课题(2012ZX08009-001)各1项,中央级公益性科研院所科研专项2项,作为研究骨干参加国家自然基金、转基因专项、973项目等多项。
先后主持转基因专项(2020ZX08009-05B)国家自然科学基金青年基金(31201531)及转基因专项子课题(2012ZX08009-001)各1项,中央级公益性科研院所科研专项2项,作为研究骨干参加国家自然基金、转基因专项、973项目多项。
授权国家发明专利:
1. 郭惠明,刘云涛,陆国清,苏晓峰,程红梅 CrSMT基因在提高植物对于生物胁迫以及非生物胁迫抗性中的用途,ZL202010607324.7;
2. 郭惠明,程红梅,孙朋卫 沙冬青干旱诱导相关基因及其表达载体和应用,ZL201310689429.1;
3. 郭惠明,齐希梁,程红梅,苏晓峰 大丽轮枝菌硫胺素转运蛋白病程关键靶基因及其干扰载体和应用,ZL201510353744.6;
4. 程红梅,郭惠明,陆国清 一种AmCBF1转录因子及其在植物抗逆方面的应用,ZL201810431980.9;
5. 苏晓峰,郭惠明,程红梅 大丽轮枝菌VdEG抗病原菌靶基因片段及其干扰载体和应用,ZL202010534157.8;
6. 程红梅,顾立江,郭惠明 沙冬青低温胁迫相关基因及其表达载体和应用,ZL201310254613.3;
7. 程红梅,齐希梁,苏晓峰,郭惠明 与抗真菌危害有关的磷脂酶靶基因片段及其在提高植物抗病性中的应用,ZL201510792509.9;
8. 苏晓峰,齐希梁,程红梅,郭惠明 大丽轮枝菌寡糖基转移酶靶基因片段及其干扰载体和应用,ZL201510792533.2;
9. 程红梅,齐希梁,苏晓峰,郭惠明 大丽轮枝菌磷脂酶靶基因片段及其干扰载体和应用, ZL201510794698.3;
10. 苏晓峰,齐希梁,郭惠明,程红梅 大丽轮枝菌 ADP-ATP 载体蛋白病程关键靶基因及其干扰载体和应用,ZL201510557932.0;
11. 苏晓峰,齐希梁,郭惠明,程红梅 大丽轮枝菌腺苷酸激酶靶基因片段及其干扰载体和应用,ZL201510791947.3;
12. 程红梅,齐希梁,郭惠明,苏晓峰 大丽轮枝菌硫胺素转运蛋白基因的敲除突变体菌株及应用,ZL201510394685.7;
近年发表的主要研究论文:
1. Chen L, Guo H*, Lin Y, ChengH. Chalcone synthase EaCHS1 from Eupatoriumadenophorum functions in salt stress tolerance in tobacco. Plant cell rep,2015, 34:885–894. (corresponding author)
2. Guo H, Li Z, Zhou M, Cheng H. cDNA-AFLP analysisreveals heat shock proteins play important roles in mediating cold, heat, anddrought tolerance in Ammopiptanthusmongolicus. Funct Integr Genomics, 2014, 14:127–133.
3. Guo H#, Lu G#, Su X, Liang G, Liu C,Cheng H. Up-regulated death-associated LIM-only protein contributes to fitnesscosts of Bacillus thuringiensisCry1Ac resistance in Helicoverpa armigera.J insect physiol, 2014, 60: 145–152.
4. Gu L, Zhang H, Guo H, ChengH. Cloning of Ammopiptanthus mongolicus C-repeat-binding factor Gene and ItsCold-induced Tolerance in Transgenic Tobacco. Braz. Arch. Biol. Technol, 2013,56(6): 895-903.
5. Pei X#, Guo H#,Wan F, Cheng H. Phenylalanine ammonia-lyase and cinnamate 4-hydroxylase genes'response to HHO in Eupatorium adenophorum.Weed Biol Manag, 2012, 12(4): 177–182. (Joint first authors)
6. Guo H, Pei X, Wan F, Cheng H. Molecular cloning ofallelopathy related genes and their relation to HHO in Eupatorium adnophorum. Mol Biol Rep, 2011, 38(7): 4651-4656.
7. Guo H, Zhang Y, Wan F, Cheng H.Agrobacterium-mediated transformation of Eupatoriumadenophorum. Plant Cell Tiss Organ Cult, 2010, 103: 417-422.
8. Chen L, Guo H, LinY, Wu Y,Gheng H. Molecular cloning and characterization of the cinnamate 4-hydroxylasegene from Eupatorium adenophorum.Weed Biol Manag, doi:10.1111/wbm.12044
9. Su, X.#, Lu, G.#, Guo, H., Zhang, K., Li, X., Cheng, H*. (2018) The dynamic transcriptomeand metabolomics profiling in Verticilliumdahliae inoculated Arabidopsisthaliana. Scientific Reports 8: 15404-15414.
10. Su, X.#, Lu, G.#, Rehman, L., Li, X., Sun, L., Guo, H., Cheng, H*. (2018)mCherry-labeled Verticillium dahliaecould be utilized to investigate its pathogenicity process in Nicotiana benthamiana. Genes 9: 508-520.
11. Su, X.#, Rehman, L., Guo,H., Li, X., and Cheng, H*. (2018). The oligosaccharyl transferase subunitSTT3 mediates fungal development and is required for virulence in Verticillium dahliae. Current Genetics 64:235-246.
12. Qi, X.#, Li, X. #, Guo, H., Guo, N., Cheng, H*. (2018). VdPLP, a patatin-likephospholipase in Verticillium dahliae,is involved in cell wall integrity and required for pathogenicity. Genes 9:162-178.
13. Rehman, L.#, Su, X.#, Li, X., Qi, X., Guo, H., and Cheng, H*. (2018). FreB isinvolved in the ferric metabolism and multiple pathogenicity-related traits of Verticillium dahliae. Current Genetics64: 645-659.
14. Su, X.#, Rehman, L., Guo,H., Li, X., Zhang, R.*, and Cheng, H*. (2017). AAC as a potential targetgene to control Verticillium dahliae.Genes 8: 25-41.
15. Rehman, L.#, Su, X.#, Guo, H., Qi, X., and Cheng, H*. (2016) Protoplast transformation asa potential platform for exploring gene function in Verticillium dahliae. BMC Biotechnology 16: 57-65.
16. Qi, X.#, Su, X., Guo,H., Qi, X., and Cheng, H*. (2016) Vdthit, a thiamine transport protein, isrequired for pathogenicity of the vascular pathogen Verticillium dahliae. Molecular Plant-Microbe Interaction 29:545-559.
17. Qi, X.#, Su, X., Guo,H., Qi, J., and Cheng, H*. (2015). A ku70 null mutant improves genetargeting frequency in the fungal pathogen Verticilliumdahliae. World Journal of Microbiology & Biotechnology 31: 1889-1897.
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