学习经历：

2003.9-2006.7 西北农林科技大学，博士

2000.9-2003.7 西北农林科技大学，硕士

1996.9-2000.7 山东农业大学，学士

工作经历：

2009.9-至今 中国农业科学院，饲料研究所

2019.1-2020.1 昆士兰大学，访问学者

2006.9-2009.8 北京林业大学，博士后

研究内容：

1）活性小分子对大肠杆菌、肠炎沙门氏菌等G‒病原菌杀菌机理的研究，应用细胞学、分子生物学及组学等技术分别从细胞、基因和蛋白水平研究生物活性分子诱导畜禽腹泻致病菌G−类细胞凋亡及其类凋亡机制；

2）活性小分子定点定向设计、分子改造、合成及其修饰，建立与内毒素结合域的关键序列，并建立内毒素血症、病原菌肠炎模型。

3）抗猫过敏制剂的创制，研究特异性阻隔分子设计、制备及其功效。

获奖情况：

2020年，颐和青年创新奖

2019年，中华农业科技一等奖（第4完成人）

2017年，北京市科学技术奖一等奖（第5完成人）

2014年，北京市科学技术奖三等奖（第3完成人）

2013年，第八届大北农科技奖（第2完成人）

学术兼职：

Front Cell Infect Microbiol, Guest Associate Editor (2021-)

Antibiotics, Topical Editor (2021-)

Marine Drugs, Editor (2021-)

培养学生：

北京市优秀毕业生1名、中国农业科学院优秀毕业生1名、中国农业科学院优秀硕士学位论文1名。

代表性研究论文：

1) Han HH, Teng D, Mao RY, Hao Y, Yang N, Wang ZL, Li T, Wang XM*, Wang JH*. Marine peptide-N6NH2 and its derivative-GUON6NH2 have potent antimicrobial activity against intracellular Edwardsiella tarda in vitro and in vivo. Front Microbiol, 2021,12: 637427. (Q2, IF5.64)

2) Li T, Wang ZL, Han HH, Teng D, Mao RY, Hao Y, Yang N, Wang XM*, Wang JH*. Dual antibacterial activities and biofilm eradication of a marine peptide-N6NH2 and its analogs against multidrug-resistant Aeromonas veronii. Int J Mol Sci, 2020, 21: 9637. (Q2, IF5.923)

3)  Li T, Teng D, Mao RY, Hao Y, Wang XM*, Wang JH*. A critical review of antibiotic resistance in probiotic bacteria. Food Res Int, 2020, 36: 109571. (Q2, IF6.475)

4)  Wang ZL, Liu XH, Teng D, Mao RY, Hao Y, Yang N, Wang X, Li ZZ, Wang XM*, Wang JH*. Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli. Commu Bio, 2020,3(1), 41. (Q2, IF5.489)

5) Han HH, Li T, Wang ZL, Teng D, Mao RY, Hao Y, Yang N, WangXM*, Wang JH*. Improved stability and activity of a marine peptide-N6NH2against Edwardsiella tarda and its preliminaryapplication in fish. Mar Drugs, 2020, 18: 650. 5.118 (Q2, IF5.118)

6) Han HH, Wang ZL, Li T, Teng D, Mao RY, Hao Y, Yang N, Wang XM*,Wang JH*. Recent progress of bacterial FtsZ inhibitors with a focus on peptides.J FEBS, 2020, 288 (4): 1091-1106. (Q2, IF5.542)

7) Li ZZ, Teng D, Mao RY, HaoY, Wang X, Wang XM*, Wang JH*. Improved antibacterial activity of themarine peptide N6 against intracellular Salmonella Typhimurium byconjugating with the cell-penetrating peptide Tat11 via a cleavable linker. J Med Chem, 2018, 61(17), 7991-8000. (Q2, IF7.446)

8) Li ZZ, Mao RY, Teng D, HaoY, Chen HX, Wang XM*, Wang JH*. Improved antibacterial activity of amarine peptide-N2 against intracellular Salmonella typhimurium byconjugating with cell-penetrating peptides-bLFcin6/Tat11. Eur J Med Chem, 2017,145, 263.(Q2, IF6.514)

9) Wang XM, Teng D, Mao RY, Yang N, Hao Y, Wang JH*. Combined systems approaches reveal a multistage mode of action of a marine antimicrobial peptide against pathogenic Escherichia coli and its protective effect against bacterial peritonitis and endotoxemia. Antimicrob Agents Chemother, 2016, 61(1). pii, e01056-16.(Q2, IF5.191)

10) Wang XM, Teng D, Guan QF, Tian F, Wang JH*. Detection of genetically modified crops using multiplex asymmetric polymerase chain reaction and asymmetric hyperbranched rolling circle amplification coupled with reverse dot blot. Food Chem, 2015, 173: 1022-1029. (Q2, IF7.514)

11) Wang XM, Teng D, Guan QF, Tian F, Wang JH*. Detection of Roundup Ready soybean by loop-mediated isothermal amplification combined with a lateral-flow dipstick. Food Control, 2013, 29: 213-220. (Q2, IF5.548)

12) Wang XM, Teng D, Guan QF, Tian F, Wang JH*. Comparison of three DNA extraction methods for feed products and four amplification methods for the 5´-junction fragment of Roundup Ready soybean. J Agri Food Chem, 2012,60(18): 4586-4595. (Q1, IF5.279)