导师风采
游均
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个人信息

Personal Information

  • 副研究员
  • 导师类别:硕士生导师
  • 性别: 男
  • 学历:博士研究生
  • 学位:博士

联系方式

Contact Information

  • 所属院系:油料所
  • 所属专业: 作物遗传育种  、 农艺与种业
  • 邮箱 : junyou@caas.cn
  • 工作电话 : 027-86711856

个人简介

Personal Profile

游均,博士,副研究员,硕士生导师,中国农业科学院油料作物研究所芝麻与特色油料遗传育种创新团队执行首席。主要从事芝麻品质和抗逆分子育种研究。主持国家重点研发计划子课题、国家自然科学基金、湖北省重点研发计划等多个科研项目,初步揭示了芝麻油脂及其组分、功能活性成分芝麻素、褪黑素等含量变异的遗传基础;初步探明了芝麻抗旱、耐渍、耐盐的分子机制,全基因组解析了芝麻根系性状遗传基础,发掘出一批抗旱、耐渍和根系发育等性状基因位点;率先在芝麻中实现了CRISPR/Cas9介导的基因编辑;发表论文70余篇,其中以第一或通讯作者(含共同)在Plant Biotechnology Journal、Journal of Advanced Research、Plant Physiology、Journal of Experimental Botany等杂志发表SCI论文40余篇,单篇最高影响因子13.263;获授权发明专利12项,实用新型专利4项;参与育成芝麻新品种16个,发布行业标准1项。

具体研究方向

(1)芝麻种子发育与营养品质形成的遗传基础和调控网络研究;

(2)芝麻非生物逆境抗性调控基因及其分子机制:

(3)基于基因编辑技术的芝麻种质创制与分子育种。


  • 研究方向Research Directions
分子育种
2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。
团队展示

芝麻与特色油料遗传育种创新团队,以创新品种资源和有效利用为目标,主要开展芝麻、向日葵、苏子、红花、蓖麻、胡麻等特色油料种质资源收集评价、重要农艺性状基因发掘、优质高产抗逆适宜机械化新品种选育等研究。团队现有工作人员24人,包括首席1人、骨干6人等,其中研究员4人、副研4人、产业体系岗位专家3人,院青年英才1人,8人具博士学位。团队/研究室现收集保存特色种质资源19000余份,完成了芝麻基因组解析,挖掘出一批重要基因,育成品种40多个,发表论文150余篇,获发明专利12项、软著权6项、新品种权1项,制定行业标准2项,著作9部,获科技成果奖6项,其中省部级一等奖2项。新4楼2-1

新4楼3-1

新4楼4-1


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科研项目

1、国家重点研发计划项目子课题,多功能苏子、红花品种选育与示范应用,2025-2027,主持

2、湖北省国际合作项目,优质高产芝麻品种选育与示范,2024EHA055,2024-2026,主持

3、湖北省引进外国人才和智力项目(高端外国专家项目),芝麻现代育种关键种质创新与基因发掘,2024DJC011,2024,主持

4、湖北省重点研发计划(国际合作领域),高产抗旱适宜机械化芝麻品种选育及示范,2020BHB028,2020-2022,主持

5、农业部中央级公益性科研院所基本科研业务费专项,芝麻逆境应答基因网络构建及抗旱基因挖掘,1610172018007,2018-2020,主持

6、国家自然科学基金青年基金,水稻OsSRO1c基因在干旱胁迫诱导的叶片衰老中的功能研究,31500223,2016-2018,主持


发表论文

以第一或通讯作者发表论文40余篇,影响因子大于10的论文3篇。

1.     Kefale H†,Zhou R†, Luo Z, Dossou SSK, Berhe M, Wang L, Abbas AA, Zhang Y, Zhou T, You J*, Wang L*. Metabolomic and biochemical insights into bioactive compoundsand antioxidant properties of black oilseed testa and peeled seeds. Curr Res Food Sci. 2025, 10:100939. https://doi.org/10.1016/j.crfs.2024.100939

2.     Zhou J, Hu F, Berhe M, Zhou R, Li D, Li H,Yang L, Zhou T, Zhang Y, Wang L*, You J*. Genome-wide identification, classification, and expression profiling of LACgene family in sesame. BMC Plant Biol. 2024,24:1254. https://doi.org/10.1186/s12870-024-05982-w

3.     DossouSSK†, Luo Z†, Deng Q, Zhou R, Zhang Y, Li D, Li H, TozoK, You J*, Wang L*. Biochemical and molecular insights into variation insesame seed antioxidant capability as revealed by metabolomics andtranscriptomics analysis. Antioxidants. 2024, 13(5):514. https://doi.org/10.3390/antiox13050514

4.     Li H†,Hu F†, Zhou J, Yang L, Li D, Zhou R, Zhou T, Zhang Y, Wang L*, You J*. Genome-wide characterization of the DIR gene family in sesame revealsthe function of SiDIR21 in lignan biosynthesis. Plant Physiol Biochem. 2024,217:109282. https://doi.org/10.1016/j.plaphy.2024.109282

5.     Song S†,Dossou SSK†, Meng M†, Sheng C, Li H, Zhou R, Li D, Xu P, You J*, Wang L*. Five improved sesame reference genomes and genome resequencingunveil the contribution of structural variants to genetic diversity andyield-related traits variation. Plant Biotechnol J. 2023, 21:1722-1724. https://dx.doi.org/10.1111/pbi.14092

6.     Wang X†,Wang S†, Lin Q†, Lu J, Lv S, Zhang Y, Wang X, Fan W, LiuW, Zhang L*, Zhang X*, You J*, Cui P*, Li P*. The wild allotetraploidsesame genome provides novel insights into evolution and lignan biosynthesis. J Adv Res. 2023, 50:13-24. https://dx.doi.org/10.1016/j.jare.2022.10.004

7.     Kefale H,Dossou SSK, Li F, Jiang N, Zhou R, Wang L, Zhang Y, Li D, You J*, Wang L*. Widely targeted metabolic profiling provides insights into variations inbioactive compounds and antioxidant activity of sesame, soybean, peanut, andperilla, Food Res Int. 2023, 174:113586. https://doi.org/10.1016/j.foodres.2023.113586

8.     Sheng C,Song S, Zhou W, Dossou SSK, Zhou R, Zhang Y, Li D, You J*, Wang L*.Integrating transcriptome and phytohormones analysis provided insights intoplant height development in sesame. Plant Physiol Biochem. 2023, 198:107695. https://dx.doi.org/10.1016/j.plaphy.2023.107695

9.     Dossou SSK†,Song S†, Liu A, Li D, Zhou R, Berhe M, Zhang Y, Sheng C, Wang Z, You J*, Wang L*. Resequencing of 410 sesame accessions identifies SINST1 as themajor underlying gene for lignans variation. Int J Mol Sci. 2023, 24:1055. https://dx.doi.org/10.3390/ijms24021055

10.     Li H, Tahir Ul Qamar M, Yang L, Liang J, You J*, Wang L*. Current progress, applications and challenges of multi-omicsapproaches in sesame genetic improvement. Int J Mol Sci. 2023, 24:3105. https://dx.doi.org/10.3390/ijms24043105

11.     Dossou SSK†, Luo Z†, WangZ, Zhou W, Zhou R, Zhang Y, Li D, Liu A, Dossa K, You J*, Wang L*. Thedark pigment in the sesame (Sesamum indicum L.) seed coat: isolation,characterization, and its potential precursors. Front Nutr. 2022, 9:858673. https://dx.doi.org/10.3389/fnut.2022.858673

12.     You J*, Li D, Yang L, Dossou SSK, Zhou R, Zhang Y,Wang L*. CRISPR/Cas9-mediated efficient targeted mutagenesis in sesame (Sesamum indicum L.). Front Plant Sci. 2022, 13:935825. https://dx.doi.org/10.3389/fpls.2022.935825

13.     Wang X†, You J†*, Liu A, Qi X, Li D,Zhao Y, Zhang Y, Zhang L*, Zhang X*, Li P*. Variation in melatonin contents andgenetic dissection of melatonin biosynthesis in sesame. Plants (Basel). 2022,11:2005. https://doi.org/10.3390/plants11152005

14.     Zhou W†, Song S†, DossouSSK, Zhou R, Wei X, Wang Z, Sheng C, Zhang Y, You J*, Wang L*.Genome-wide association analysis and transcriptome reveal novel loci and acandidate regulatory gene of fatty acid biosynthesis in sesame (Sesamum indicumL.). Plant Physiol Biochem. 2022, 186:220-231. https://dx.doi.org/10.1016/j.plaphy.2022.07.023

15.     Su R, Dossou SSK, Dossa K, Zhou R, Liu A, ZhongY, Fang S, Zhang X, Wu Z*, You J*. Genome-wide characterization andidentification of candidate ERF genes involved in various abiotic stressresponses in sesame (Sesamum indicum L.). BMC Plant Biol. 2022, 22: 256 http://dx.doi.org/10.1186/s12870-022-03632-7

16.     Dossa K*, Zhou R, Li D, Liu A, Qin L, Mmadi MA,Su R, Zhang Y, Wang J, Gao Y, Zhang X*, You J*. A novel motif in the5'-UTR of an orphan gene 'Big Root Biomass' modulates root biomass in sesame.Plant Biotechnol J. 2021, 19:1065-1079. https://dx.doi.org/10.1111/pbi.13531

17.     Wang L†, Dossa K†, You J†, Zhang Y, Li D, Zhou R, Yu J, Wei X, Zhu X, Jiang S, Gao Y, Mmadi MA, Zhang X*. High-resolution temporal transcriptome sequencing unravelsERF and WRKY as the master players in the regulatory networks underlying sesameresponses to waterlogging and recovery. Genomics. 2021, 113:276-290. https://dx.doi.org/10.1016/j.ygeno.2020.11.022

18.     Liu A, Wei M, Zhou Y, Li D, Zhou R, Zhang Y,Zhang X, Wang L*, You J*. Comprehensive analysis of SRO gene family inSesamum indicum (L.) reveals its association with abiotic stress responses. IntJ Mol Sci. 2021, 22:13048. https://doi.org/10.3390/ijms222313048

19.     Zhang Y*, Gong H, Li D, Zhou R, Zhao F, Zhang X, You J*. Integrated small RNA and Degradomesequencing provide insights into salt tolerance in sesame (Sesamum indicum L.).BMC Genomics. 2020, 21: 494. https://doi.org/10.1186/s12864-020-06913-3

20.     Dossa K†, You J†, Wang L†, Zhang Y, Li D, Zhou R, Yu J, Wei X, Zhu X, Jiang S, Gao Y, Mmadi MA, Zhang X*. Transcriptomic profiling of sesame during waterlogging andrecovery. Sci Data. 2019, 6:204. https://dx.doi.org/10.1038/s41597-019-0226-z

21.     You J, Zhang Y, Liu A, Li D, Wang X, Dossa K, ZhouR, Yu J, Zhang Y, Wang L, Zhang X*. Transcriptomic and metabolomic profiling ofdrought-tolerant and susceptible sesame genotypes in response to droughtstress. BMC Plant Biol. 2019, 19:267. https://dx.doi.org/10.1186/s12870-019-1880-1

22.    Zhang Y, Li D, Zhou R, Wang X, Dossa K, Wang L, Zhang Y, Yu J, Gong H, Zhang X*, You J*.Transcriptome and metabolome analyses of two contrasting sesame genotypesreveal the crucial biological pathways involved in rapid adaptive response tosalt stress. BMC Plant Biol. 2019, 19:66. https://dx.doi.org/10.1186/s12870-019-1665-6

23.     Zhang Y, Wei M, Liu A, Zhou R, Li D, Dossa K,Wang L, Zhang Y, Gong H, Zhang X*, You J*. Comparative proteomicanalysis of two sesame genotypes with contrasting salinity tolerance inresponse to salt stress. J Proteomics. 2019, 201:73-83. https://dx.doi.org/10.1016/j.jprot.2019.04.017

24.     Wei M, Liu A, Zhang Y, Zhou Y, Li D, Dossa K,Zhou R, Zhang X*, You J*. Genome-wide characterization and expressionanalysis of the HD-Zip gene family in response to drought and salinity stressesin sesame. BMC Genomics. 2019, 20:748. https://dx.doi.org/10.1186/s12864-019-6091-5

25.     You J, Wang Y, Zhang Y, Dossa K, Li D, Zhou R, WangL, Zhang X*. Genome-wide identification and expression analyses of genesinvolved in raffinose accumulation in sesame. Sci Rep. 2018, 8:4331. https://dx.doi.org/10.1038/s41598-018-22585-2

26.     Wang Y, Zhang Y, Zhou R, Dossa K, Yu J, Li D,Liu A, Mmadi MA, Zhang X, You J*. Identification and characterization ofthe bZIP transcription factor family and its expression in response to abioticstresses in sesame. PLoS One. 2018, 13:e0200850. https://dx.doi.org/10.1371/journal.pone.0200850

27.     Zhang Y, Li D, Wang Y, Zhou R, Wang L, Zhang Y,Yu J, Gong H, You J*, Zhang X*. Genome-wide identification andcomprehensive analysis of the NAC transcription factor family in Sesamumindicum. PLoS One. 2018, 13:e0199262. https://dx.doi.org/10.1371/journal.pone.0199262

28.     You J and Chan Z*. ROSregulation during abiotic stress responses in crop plants. Front Plant Sci. 2015, 6:1092. https://doi.org/10.3389/fpls.2015.01092

29.     You J, Zhang L, Song B, Qi X, Chan Z*. Systematicanalysis and identification of stress-responsive genes of the NAC gene familyin Brachypodium distachyon. PLoS ONE. 2015, 10(3):e0122027. http://dx.doi.org/10.1371/journal.pone.0122027

30.     Zhang L†, You J†, Chan Z*. Identification and characterization of TIFY family genes in Brachypodium distachyon. J Plant Res. 2015,128:995-1005. http://dx.doi.org/10.1007/s10265-015-0755-2

31.     You J, Zong W, Hu H, Li X, Xiao J, Xiong L*. ASTRESS-RESPONSIVE NAC1-regulated protein phosphatase gene rice proteinphosphatase18 modulates drought and oxidative stress tolerance through abscisicacid-independent reactive oxygen species scavenging in rice. Plant Physiol. 2014, 166: 2100-2114. http://dx.doi.org/10.1104/pp.114.251116

32.     You J, Zong W, Du H, Hu H, Xiong L*. A specialmember of the rice SRO family, OsSRO1c,mediates responses to multiple abiotic stresses through interaction withvarious transcription factors. Plant Mol Biol.2014, 84: 693-705. http://dx.doi.org/10.1007/s11103-013-0163-8

33.     You J, Zong W, Li X, Ning J, Hu H, Li X, Xiao J,Xiong L*. The SNAC1-targeted gene OsSRO1cmodulates stomatal closure and oxidative stress tolerance by regulatinghydrogen peroxide in rice. J Exp Bot.2013, 64: 569-83. 5.36. http://dx.doi.org/10.1093/jxb/ers349

34.     You J, Hu H, Xiong L*. An ornithineδ-aminotransferase gene OsOAT confers drought and oxidative stresstolerance in rice. Plant Sci. 2012, 197: 59-69. http://dx.doi.org/10.1016/j.plantsci.2012.09.002

35.    Zhou W†, Sheng C†, Dossou SSK, Wang Z, Song S, You J*, Wang L*. Genome-wideidentification of TPS genes in sesame and analysis of their expression inresponse to abiotic stresses. Oil Crop Science. 2023, 8:81-88. https://dx.doi.org/10.1016/j.ocsci.2023.03.004

36.     Zhang Y, Li D, Zhou R, Liu A, Wang L, Zhang Y,Gong H, Zhang X*, You J*. A collection of transcriptomic and proteomicdatasets from sesame in response to salt stress. Data Brief. 2020, 32:106096. https://dx.doi.org/10.1016/j.dib.2020.106096

37.     You J, Li Q, Yue B, Xue WY, Luo LJ, Xiong LZ*.Identification of quantitative trait loci for ABA sensitivity at seedgermination and seedling stages in rice. J Genet Genomics.2006, 33:532-41. http://dx.doi.org/10.1016/S0379-4172(06)60082-6

38.     杨茜†, 游均†, 周瑢, 方圣, 张艳欣, 吴自明*, 王林海*. 芝麻籽粒植酸含量高通量检测方法的建立与低植酸种质的筛选. 中国农业科学. 2024, 57(12):2282-2294. https://doi.org/10.3864/j.issn.0578-1752.2024.12.002

39.     周江龙, 胡凤铎, 周瑢, 周王易, 王志坚, 黎冬华, 张艳欣, 王林海*, 游均*. 芝麻种质资源矿质元素含量和品质性状分析与综合评价. 中国油料作物学报. 2024. https://doi.org/10.19802/j.issn.1007-9084.2023322

40.     周江龙,胡凤铎,裴庆华,周瑢,韩亮,张艳欣,王林海*,游均*. 不同黑芝麻富硒能力及营养品质性状分析. 中国油料作物学报.2024, 网络首发. https://doi.org/10.19802/j.issn.1007-9084.2024194

41.     苏如奇, 黎冬华, 吴自明, 王林海, 游均*. 芝麻非生物胁迫抗性研究进展. 中国油料作物学报.2024, 网络首发.https://doi.org/10.19802/j.issn.1007-9084.2024041

42.     游均, 郭元章, 赵应忠, 王林海*. 栽培芝麻分布、起源与驯化. 中国油料作物学报. 2024, 46(5):959-968. https://doi.org/10.19802/j.issn.1007-9084.2023065

43.     张玉娟, 黎冬华, 宫慧慧, 崔新晓, 高春华, 张秀荣, 游均*, 赵军胜*. 芝麻NAC转录因子基因SiNAC77的克隆及耐盐功能分析. 生物技术通报. 2023, 39(11):308-317. https://doi.org/10.13560/j.cnki.biotech.bull.1985.2023-0096

44.     罗自舒, 王志坚, 周王易, Senouwa Segla Koffi Dossou, 周瑢, 张艳欣, 黎冬华, 游均*, 王林海*. 不同颜色芝麻营养品质性状遗传变异分析. 植物遗传资源学报. 2023, 24(2):365-375. https://doi.org/10.13430/j.cnki.jpgr.20220919001

45.     魏梦园, 刘爱丽, 黎冬华, 周瑢, 王林海, 张秀荣, 游均*. 芝麻CCCH锌指蛋白基因SiC3H1的克隆及表达分析. 分子植物育种. 2020, 18(24):7982-7988. https://doi.org/10.13271/j.mpb.018.007982

46.     刘爱丽, 魏梦园, 黎冬华, 周瑢, 张秀荣, 游均*. 芝麻肌醇半乳糖苷合成酶基因SiGolS6的克隆及功能分析. 中国农业科学. 2020, 53(17):3432-3442. https://doi.org/10.3864/j.issn.0578-1752.2020.17.002

 


授权专利

授权发明专利

1. OsOAT基因在控制水稻抗旱性及抗重金属汞中的应用. ZL201210138418X

2. OsPP18基因在控制水稻抗旱性中的应用.ZL201110321661.0

3. OsSRO1c基因在控制水稻抗旱性中的应用. ZL201110083226.9

4. 一种适用于芝麻联合收获的装置. ZL201910541664.1

5. 芝麻蛋白SiLLR在调控植物根系发育中的应用. ZL202010655770.5

6. 芝麻蛋白SiBRB在调控植物根系发育中的应用. ZL202010656166.4

7. 芝麻抗旱、耐湿与耐盐基因SiNAC56及其编码的蛋白与应用. ZL201811408071.X

8. 一种应用于芝麻催枯的干燥剂. ZL201910773119.5

9. 芝麻SiWRKY67基因在调控褪黑素合成中的应用. ZL202110764450.8

10. 一种高效机械化联合收获芝麻的方法. ZL202010748085.7

11. 一种快速高效的芝麻毛状根遗传转化体系的建立方法.ZL202010887616.0

12. 芝麻SiERF103基因在增强植物抗性中的应用. ZL202111094686.1


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