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宋英,女,博士,研究员,博士生导师,2006年博士毕业于中国科学院水生生物研究所;2008-2013年在美国莱斯大学(Rice University)生态与进化生物系开展博士后研究,2013年12月进入中国农业科学院植物保护研究所工作。
研究内容主要围绕鼠类抗药性和季节性繁殖现象,利用高通量二代基因组测序技术,整合生物信息学、表观遗传学、分子生态学等学科的理论和方法,研究鼠类产生抗药性和季节性繁殖现象的分子遗传学和表观遗传学机制。主要内容包括我国主要鼠类产生抗药性的分子遗传和表观遗传机制,构建我国主要抗性鼠类种群的特征性抗性指纹数据库,开发快速高通量鉴定抗性鼠的分子技术;调控鼠类季节性繁殖的表观遗传机制;我国鼠类种群的遗传结构和谱系地理分布特征。在Current Biology、Molecular Ecology、PNAS等杂志发表论文多篇,研究成果曾被Science、Discover Magazine, BBC News及我国的科技日报等多家杂志媒体专门撰文评论和报道。
代表性文章
1. Ma X, ChenY, Ying Y, Geng Y, Wang D, Li N, Liu X-H*, Song Y*. (2021) Sublethaldose of warfarin induction promotes the accumulation of warfarin resistance insusceptible Norway rats. J Pest Sci, 94(4):1-11.
2. Wang D#, Li N#, Tian L, Ren F, Li Z,Chen Y, Liu L, Hu X, Zhang X, Song Y*,Hut R*, Liu X*. (2019) Dynamic expressions ofhypothalamic genes regulate seasonal breeding in a natural rodent population.Mol Ecol, 28(15):3508-3522.
3. Ma X, Wang D, Li N, Liu L, Tian L, Luo C, Cong L, Feng Z, Liu X*,Song Y* (2018). Lowwarfarin resistance frequency in Norway rats in two cities in China after 30years of usage of anticoagulant rodenticides. Pest Manag Sci, 74 (11):2555-2560.
4. Chen Y#, Wang D#, Li N, Hu X, Ren F, Hao WL, Song Y, Liu X* (2018).Kinship analysis reveals reproductive success skewed toward overwinteredBrandt’s voles in semi-natural enclosures. Integrative Zoology. 14 (5) doi:10.1111/1749-4877.12330.
5. Chen Y#, Liu L,Li Z, Wang D, Li N, Song Y, Guo C,Liu X* (2017) Molecular cloning and characterization of kiss1 inBrandt's voles (Lasiopodomys brandtii). Comparative Biochemistry and PhysiologyPart B: Biochemistry and Molecular Biology, 208-209: 68-74.
6. Zeng L, Ming C, Li Y, Su L, Su Y, O OteckoN, Dalecky A, Donnellan S, Aplin K, Liu XH, Song Y, Zhibin Z, Esmailizadeh A, Sohrabi SS, Nanaei HA, Liu HQ,Wang MS, Atteynine SA, Rocamora G, Brescia F, Morand S, Irwin DM, Peng MS, YaoYG, Li H, Wu DD, Zhang YP,2017. Outof Southern East Asia of the Brown Rat Revealed by Large Scale GenomeSequencing. Mol Biol Evol, 35(1): 149~158.
7. Chen Y, Liu L, Li Z, Wang D.W., Li N, Song Y., Liu XH*. 2017. Molecular cloningand characterization of Kiss1 inBrandt’s voles (Lasiopodomys brandtii).Comp Biochem Physiol B 208–209: 68–74
8. Song Y., LanZ., Kohn M.H. 2014. Mitochondrial DNA phylogeography of the Norway rat. PLoS ONE 9:e88425.
9. Song Y.,Endepols S., Klemann N., Richter D., Matuschka F., Shih C., Nachman M. and KohnM.H. 2011. Adaptive introgression of anticoagulant rodent poison resistance byhybridization between Old World mice. CurrBiol 21 (15), 1296-1301.
10. LiuK.J., Steinberg E., Yozzo A., Song Y.,Kohn M.H., Nakhleh L. 2015. Interspecific introgressive origin of genomicdiversity in the house mouse. PNAS.112(1), 196-201.
11. LiuK.J., Dai J., Truong K., Song Y.,Kohn M.H., Nakhleh L. 2014. An HMM-Based Comparative Genomic Framework forDetecting Introgression in Eukaryotes. PLoSComput Biol 10(6): e1003649.
12. EndepolsS., Klemann N., Song Y., Kohn M.H.2012. Vkorc1 Variation in house mice during warfarin and difenacoum fieldtrials. Pest Manag Sci. 69:409-413
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