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刘文文，女，1981年4月出生，主要研究方向为植物病毒学，副研究员，硕士生导师。
2005年获得东北农业大学植物保护学学士学位，2008年获得东北农业大学植物病理学硕士学位，2013年获得中国农业科学院植物病理学博士学位。2013-2015在中国农业科学院植物保护研究所进行博士后研究工作，2014年获得中国农业科学院优秀博士后，2015年作为中国农业科学院青年英才计划D类人才进入植物保护研究所工作，并入选2017年北京市科技新星计划， 2019年为青年英才计划培育工程所级入选者。
一直从事介体昆虫传毒机制的研究工作，利用分离泛素酵母双杂交膜系统研究了水稻条纹病毒与介体灰飞虱之间的互作，获得了100多种互作的介体蛋白，并对其中两种蛋白的传毒功能进行了深入研究，研究结果分别以第一或共同第一作者发表在Molecular& Cellular Proteomics, 2015，PLoS Pathogens, 2014和PLoS Pathogens,2018。受邀以第一作者撰写了纤细病毒属的介体传毒机制进展，发表在Current opinion invirology, 2018。在PLoS Pathogens、Molecular & CellularProteomics、Journal of Proteomics和Frontiers in Microbiology等杂志发表SCI论文20余篇，主持国家自然科学基金等省部级项目4项，参加国家自然科学基金重点项目等3项。
主持和承担课题（主持和承担课题6项，经费209万元）
1. 国家自然科学基金面上项目：水稻条纹病毒逃避介体灰飞虱血淋巴免疫的机制（31772134），2018/01-2021/12，经费72万元，主持
2. 北京市科技新星计划：番茄斑萎病毒的监测及其介体传毒相关蛋白质鉴定（Z171100001117036），2017/01-2019/12，经费35万元，主持
3. 国家自然科学基金青年基金：糖转运蛋白等参与灰飞虱传播水稻条纹病毒机制的研究（31401713），2015/01-2017/12，经费25万元，主持
4. 国家重点研发计划课题：黄淮海冬小麦化肥农药减施技术集成研究与示范（2017YFD0201700），2017/01-2020/12，可支配经费50万元，课题骨干
5. 国家重点研发计划课题：北方水稻化肥农药减施技术集成研究与示范（2018YFD0200209），2018/01-2020/12，可支配经费27万元，课题骨干
6. 国家自然科学基金重点项目：水稻条纹病毒突破介体灰飞虱中肠屏障的机制（31630058），2017/01-2021/12，经费278万元，参加
1. Lu Zhang, Wenwen Liu*, Xiaowan Zhang,Li Li, Xifeng Wang. Southern rice black-streaked dwarf virus hijacks SNAREcomplex of its insect vector for its effective transmission to rice. MolecularPlant Pathology, 2021, 22 (10): 1256-1270.
2. Beatriz Moya Fernández, Wenwen Liu*, LuZhang, Jamal-U-Ddin Hajano, Xifeng Wang. Interplay of rice stripe virus andrice black streaked dwarf virus during their acquisition and accumulation ininsect vector. Viruses, 2021, 13: 1121.
3. Faliang Qin#, Wenwen Liu#, Nan Wu, Lu Zhang, Zhongkai Zhang,Xueping Zhou, Xifeng Wang. Invasion of midgut epithelial cells by apersistently transmitted virus is mediated by sugar transporter 6 in its insectvector. PLoS pathogens. 2018, 14: e1007201.
4. WenwenLiu, Stewart Gray, Yan Huo, Li Li, Taiyun Wei, XifengWang. Proteomic analysis of interaction between a plant virus and its vectorinsect reveals new functions of a hemipteran cuticular protein, MolecularCellular Proteomics, 2015, 14(8): 2229-2242.
5. WenwenLiu, Jamal-U-Ddin Hajano, Xifeng Wang. New insights onthe transmission mechanism of tenuiviruses by their vector insects. CurrentOpinion in Virology, 2018, 33: 13-17.
6. Jamal-U-Ddin Hajano, Ahmed Raza, Lu Zhang,Wenwen Liu*, Xifeng Wang. Ribavirintargets sugar transporter 6 to suppress acquisition and transmission of ricestripe tenuivirus by its vector Laodelphaxstriatellus. Pest Management Science, 2020, 76: 4086-4092.
7. Yan Huo#, Wenwen Liu#, Fujie Zhang, Xiaoying Chen, Li Li, QifeiLiu, Yijun Zhou, Taiyun Wei, Rongxiang Fang, Xifeng Wang. Transovarialtransmission of a plant virus is mediated by vitellogenin of its insect vector,PloS Pathogens, 2014, 10: e1003949.
8. Lu Zhang, Wenwen Liu*, Xifeng Wang*.Immunofluorescent labeling of plant virus and insect vector proteins inhemipteran guts. Jove-Journal of Visualized Experiments, 2021, (171).
9. WenwenLiu#, Xiaowan Zhang#, Nan Wu, Ren Ying Dang and Xifeng Wang. High diversityand functional complementation of alimentary canal microbiota ensure smallbrown planthopper to adapt different biogeographic environments. Frontiers inMicrobiology, 2020, 10: 2953.
10. Hui Wang, Nan Wu, Yan Liu, Jiban KumarKundu, Wenwen Liu* and Xifeng Wang*.Higher bacterial diversity of gut microbiota in different natural populationsof leafhopper vector does not influence WDV transmission. Frontiers inMicrobiology, 2019, 10: 1144.
11. Peipei Zhang, Wenwen Liu*, Mengji Cao, Sebastien Massart*, Xifeng Wang. Two noveltotiviruses in the white-backed planthopper, Sogatella furcifera; Journal of General Virology, 2018, 99:710-716.
12. WenwenLiu, Min Xin, Mengji Cao, Meng Qin, Shouqi Zhao, XifengWang. Identifcation, characterization and full-length sequence analysis of anovel endornavirus in common sunflower (Helianthusannuus L.). Journal of Integrative Agriculture, 2018, 17(10): 2281-2291.
13. Hui Wang, Yan Liu, Lu Zhang, Jiban KumarKundu, Wenwen Liu, Xifeng Wang. ADPribosylation factor 1 facilitates spread of wheat dwarf virus in its insectvector. Cellular Microbiology, 2019: e13047.
14. Nan Wu, Peipei Zhang, Wenwen Liu, Mengji Cao, Sebastien Massart, Xifeng Wang. Completegenome sequence and characterization of a new iflavirus from the small brownplanthopper (Laodelphax striatellus).Virus Research, 2019, 272.
15. Hui Wang, Yan Liu, Wenwen Liu, Mengji Cao, Xifeng Wang. Full genome sequence of anovel iflavirus from the leafhopper Psammotettixalienus. Archives of Virology, 2019, 164(1): 309-311.
16. Nan Wu, Peipei Zhang, Wenwen Liu, Mengji Cao, Xifeng Wang. Sequence analysis and genomicorganization of a new insect iflavirus, Sogatellafurcifera honeydew virus 1. Archives of Virology, 2018 163: 2001-2003.
17. Nan Wu, Peipei Zhang, Wenwen Liu, Xifeng Wang. Sogatella furcifera hepe-like virus: Firstmember of a novel Hepeviridae clade identified in an insect. Virus Research, 2018,250: 81-86.
18. Peipei Zhang, Yan Liu, Wenwen Liu, Mengji Cao, SebastienMassart and Xifeng Wang. Identification, characterization and full-length sequenceanalysis of a novel polerovirus associated with wheat leaf yellowing disease.Frontiers in Microbiology, 2017, 8:1689.
19. Min Xin, Mengji Cao, Wenwen Liu, Yingdang Ren, Xueping Zhou, Xifeng Wang. Twonegative-strand RNA viruses identified in watermelon represent a novel clade inthe order Bunyavirales. Frontiers in Microbiology, 2017, 8:1514.
20. Peipei Zhang, Yan Liu, Wenwen Liu, Sebastien Massart, andXifeng Wang. Simultaneous detection of wheat dwarf virus, northern cerealmosaic virus, barley yellow striate mosaic virus and rice black-streaked dwarfvirus in wheat by multiplex RT-PCR. Journal of Virological Methods, 2017, 249,170-174.
21. Min Xin, Peipei Zhang, Wenwen Liu, Yingdang Ren, Mengji Cao, XifengWang. The complete nucleotide sequence and genome organization of a novelbetaflexivirus infecting Citrulluslanatus. Archives of Virology, 2017, 162, 3239-3242.
22. Min Xin, Mengji Cao, Wenwen Liu, Yingdang Ren, Chuantao Lu, Xifeng Wang. The genomic andbiological characterization of Citrullus lanatus cryptic virus infectingwatermelon in China. Virus Research, 2017, 232, 106-112.
23. Win Than#, Faliang Qin#,Wenwen Liu, Xifeng Wang. Analysis ofSogatella furcifera proteome thatinteract with P10 protein of Southern rice black-streaked dwarf virus.Scientific Reports, 2016, 6: 32445.
24. Beibei Liu, Faliang Qin, Wenwen Liu, Xifeng Wang. Differentialproteomics profiling of the ova between healthy and Rice stripe virus-infectedfemale insects of Laodelphax striatellus.Scientific Reports, 2016, 6: 27216.
25. 刘贝贝, 刘文文*,王锡锋. 水稻条纹病毒对介体灰飞虱生长发育相关基因转录水平的影响. 植物病理学报, 2017,47: 68-74.
26. 冯超红, 刘文文,杨琳琳,王光华,任应党.沿黄稻区介体灰飞虱有效接种虫量与水稻病毒病发生关系研究.河南农业科学,2020, 49: 87-92.
27. 俎瑶琛, 刘文文,刘艳,王锡锋.基于酵母双杂交系统筛选灰飞虱体内与大麦黄条点花叶病毒核衣壳蛋白互作的蛋白质 植物病理学报, 2019,49: 226-234.
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