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陈华民，男，1973年4月出生，河南浚县人。现任中国农业科学院副研究员、硕士生导师。
1996年获沈阳农业大学农产品贮藏与加工专业学士学位，1999年获沈阳农业大学植物病理学硕士学位，2008年获上海交通大学生物化学与分子生物学博士学位。2004-2008年于北京生命研究所联合培养博士，2013-2014年于加州大学戴维斯分校访学一年。2008年-至今，中国农业科学院植物保护研究所从事科研工作。兼任北京植物病理学会理事、副秘书长，Crop Protection杂志副主编，Front Plant Sci杂志和Front Microbiol杂志编委。
陈华民长期从事植物病理学领域相关研究，早期揭示了乙烯信号途径关键转录因子EIN3EIL1通过水杨酸信号途径调控植物先天免疫的作用机制；建立了蛋白-蛋白互作的荧光素酶片段互补图像技术。当前主要以植物-细菌互作为基础，解析病害致灾机理、植物抗病机理，研发可持续发展的绿色防控技术和产品。此外，针对生产上高氮肥加重植物病害为害的实际问题，致力于植物抗病性与氮素吸收利用间关联机制的解析。研究成果曾分别在Plant Cell，Sci Adv，Plant Physiol，New Phytol，Mol Plant Pathol，Pest Manag Sci，Int J Mol Sci，MPMI，Rice，Plant Cell Physiol，Front Microbiol，Appl Environ Microbiol等杂志上发表。先后主持国家自然科学基金面上项目2项、863计划子课题1项、农业行业科研专项子课题1项，参加十三五重点研发专项、国家转基因重大专项、中国农科院创新工程等多项。
1. 国家自然科学基金委，面上项目，31972255，OsNF-YAs在osa-miR169o调控水稻抗病性和氮吸收利用中的内在作用机制研究，2020-01至2023-12，58万元，在研，主持
2. 科技部，国家重点研发计划，2017YFD0200900，作物免疫调控与物理防控技术及产品研发，2017.07至2020.12，5403万元，结题，参加
3. 农业部，转基因育种专项，2016ZX08001-002，抗病转基因水稻新品种培育，2016.06至2020.12，5907.46万元，结题，参加
4. 科技部，国家863计划，2012AA101504，农林有害生物分子免疫调控技术研究，2012.01至2015.12，630万元，结题，参加（任务主持）
5. 农业部，农业行业专项，201003066-2，西甜瓜种传细菌性果斑病综合防控技术研究与示范-果斑病菌致病机制解析，2010.07至2014.12，90万元，结题，课题主持
6. 国家自然科学基金委，面上项目，30970310，基于烟草瞬时表达的萤火虫荧光素酶片段互补图像技术的研究及在水稻MAPKs和MAPKKs互作研究中的应用，2010.01至2012.12，30万元，结题，主持
发表论文：
1．Yu, C.†; Nguyen, D.P.†; Yang, F.;Shi, J.; Wei, Y.; Tian, F.; Zhao, X.*; Chen, H.*,Transcriptome analysis revealed overlapping and special regulatory roles of RpoN1and RpoN2 in motility, virulence, and growth of Xanthomonas oryzae pv. oryzae."Front Microbiol 2021, 12: 653354.
2．Yu, C.; Yang, F.;Xue, D.; Wang, X. and Chen, H.*, The Regulatory Functions of sigma(54)Factor in Phytopathogenic Bacteria. Int J Mol Sci 2021, 22(23): 12692.
3．Li, Y.†, Jiao, Y.†,Shi, J., Xie, J., Yin, J., Zhao, X.*; Chen, H.*, BLB8, an antiviralprotein from Brevibacillus laterosporus strain B8, inhibits Tobaccomosaic virus infection by triggering immune response in tobacco. PestManag Sci 2021, 77(10): 4383-4392.
4．Weiwei Yan, YimingWei, Susu Fan, Chao Yu, Fang Tian, QiWang, Fenghuan Yang*, and Huamin Chen.Diguanylate Cyclase GdpX6 with c-di-GMP Binding Activity Involved in theRegulation of Virulence Expression in Xanthomonas oryzae pv. oryzae.Microorganisms 2021, 9(3): 495.
5．Shahbaz, M.U.†; Qian,S.†; Yun, F.†; Zhang, J.; Yu, C.; Tian, F.; Yang F.*; Chen H.*, 2020.Identification of the regulatory components mediated by the Cyclic di-GMP receptorFilp and its interactor PilZX3 and functioning in virulence of Xanthomonasoryzae pv. oryzae. Mol Plant Microbe Interact 2020, 33(10):1196-1208.
6．Yu, C.; Nguyen, D. P.;Ren, Z.; Liu, J.; Yang, F.; Tian, F.; Fan, S.; Chen, H.*, The RpoN2-PilRX regulatory system governs type IV pilusgene transcription and is required for bacterial motility and virulence in Xanthomonasoryzae pv. oryzae. Mol Plant Pathol 2020, 21 (5): 652-666.
7．Li, H.; Xue, D.;Tian, F.*; Yuan, X.; Yang, F.; Chen, H.; Hutchins, W.; Yang, C. H.; He,C.*, Xanthomonas oryzae pv. oryzae response regulator TriPregulates virulence and exopolysaccharide production via interacting withc-di-GMP phosphodiesterase PdeR. Mol Plant Microbe Interact 2019, 32(6):729-739.
8．Yu, C.; Chen, Y.;Cao, Y.; Chen, H.*; Wang, J.; Bi, Y. M.; Tian, F.; Yang, F.; Rothstein,S. J.; Zhou, X.; He, C., Overexpression of miR169o, an Overlapping MicroRNA inResponse to Both Nitrogen Limitation and Bacterial Infection, Promotes NitrogenUse Efficiency and Susceptibility to Bacterial Blight in Rice. Plant CellPhysiol 2018, 59 (6): 1234-1247.
9．Yu, C.; Chen, H.;Tian, F.; Yang, F.; Yuan, X.; Yang, C. H.; He, C.*, A ten gene-containinggenomic island determines flagellin glycosylation: implication for itsregulatory role in motility and virulence of Xanthomonas oryzae pv. oryzae.Mol Plant Pathol 2018, 19 (3): 579-592.
10． Xue, D.; Tian, F.*;Yang, F.; Chen, H.; Yuan, X.; Yang, C. H.; Chen, Y.; Wang, Q.; He, C.,Phosphodiesterase EdpX1 Promotes Xanthomonas oryzae pv. oryzaeVirulence, Exopolysaccharide Production, and Biofilm Formation. Appl EnvironMicrobiol 2018, 84 (22): e01717-18.
11．Qin, J.; Zhou, X.;Sun, L.; Wang, K.; Yang, F.; Liao, H.; Rong, W.; Yin, J.; Chen, H.;Chen, X.*; Zhang, J.*, The Xanthomonas effector XopK harbours E3ubiquitin-ligase activity that is required for virulence. New Phytol 2018,220 (1): 219-231.
12．Yu, C.; Chen, H.;Tian, F.; Yang, F.; He, C., RpoN2- and FliA-regulated fliTX is indispensiblefor flagellar motility and virulence in Xanthomonas oryzae pv. oryzae.BMC Microbiol 2017, 17 (1): 171.
13．Fan, S.; Tian, F.*;Li, J.; Hutchins, W.; Chen, H.; Yang, F.; Yuan, X.; Cui, Z.; Yang, C. H.*;He, C., Identification of phenolic compounds that suppress the virulence of Xanthomonasoryzae on rice via the type III secretion system. Mol Plant Pathol2017, 18 (4): 555-568.
14．Yang, F.; Qian, S.;Tian, F.; Chen, H.; Hutchins, W.; Yang, C. H.; He, C.*, The GGDEF-domainprotein GdpX1 attenuates motility, exopolysaccharide production and virulencein Xanthomonas oryzae pv. oryzae. J Appl Microbiol 2016,120 (6): 1646-57.
15．Thomas, N. C.†; Schwessinger, B.†; Liu, F.; Chen, H.; Wei, T.; Nguyen, Y. P.; Shaker, I. W. F.;Ronald, P. C.*, XA21-specific induction of stress-related genes following Xanthomonasinfection of detached rice leaves. PeerJ 2016, 4: e2446.
16．Yu, C.†; Wang, N.†; Wu, M.; Tian, F.; Chen, H.; Yang, F.; Yuan, X.; Yang, C. H.;He, C.*, OxyR-regulated catalase CatB promotes the virulence in rice viadetoxifying hydrogen peroxide in Xanthomonas oryzae pv. oryzae. BMCMicrobiol 2016, 16 (1): 269.
17．Yu, C.†; Chen, H. M.†; Tian, F.; Bi,Y. M.; Steven, R. J.; Jan, L. E.; He, C. Y.*, Identification ofdifferentially-expressed genes of rice in overlapping responses to bacterialinfection by Xanthomonas oryzae pv. oryzae and nitrogendeficiency. Journal of Integrative Agriculture 2015, 14 (5): 888-899.
18．Yang, F.; Tian, F.; Chen, H.; Hutchins, W.; Yang, C. H.; He, C.*,The Xanthomonas oryzae pv. oryzae PilZ Domain Proteins FunctionDifferentially in Cyclic di-GMP Binding and Regulation of Virulence andMotility. Appl Environ Microbiol 2015, 81 (13): 4358-67.
19．Kang, S.; Yang, F.; Li, L.; Chen, H.; Chen, S.; Zhang, J.*, TheArabidopsis transcription factor BRASSINOSTEROID INSENSITIVE1-ETHYLMETHANESULFONATE-SUPPRESSOR1 is a direct substrate of MITOGEN-ACTIVATED PROTEINKINASE6 and regulates immunity. Plant physiology 2015, 167 (3): 1076-86.
20．Li, H.; Yu, C.; Chen, H.; Tian, F.*; He, C., PXO_00987, aputative acetyltransferase, is required for flagellin glycosylation, andregulates flagellar motility, exopolysaccharide production, and biofilmformation in Xanthomonas oryzae pv. oryzae. Microb Pathog2015, 85: 50-7.
21．Tian, F.; Yu, C.; Li, H.; Wu, X.; Li, B.; Chen, H.; Wu, M.; He,C.*, Alternative sigma factor RpoN2 is required for flagellar motility and fullvirulence of Xanthomonas oryzae pv. oryzae. Microbiol Res2015, 170: 177-83.
22．Pruitt, R. N.†; Schwessinger, B.†*; Joe, A.; Thomas, N.; Liu, F.; Albert, M.; Robinson, M. R.;Chan, L. J. G.; Luu, D. D.; Chen, H.; Bahar, O.; Daudi, A.; DeVleesschauwer, D.; Caddell, D.; Zhang, W.; Zhao, X.; Li, X.; Heazlewood, J. L.;Ruan, D.; Majumder, D.; Chern, M.; Kalbacher, H.; Midha, S.; Patil, P. B.;Sonti, R. V.; Petzold, C. J.; Liu, C. C.; Brodbelt, J. S.; Felix, G.; Ronald,P. C.*, The rice immune receptor XA21 recognizes a tyrosine-sulfated proteinfrom a Gram-negative bacterium. Science Advances 2015, 1 (6): e1500245.
23．Yu, C.†; Chen, H.†; Tian, F.;Leach, J. E.; He, C.*, Differentially-expressed genes in rice infected by Xanthomonas oryzae pv. oryzae relative to aflagellin-deficient mutant reveal potential functions of flagellin inhost-pathogen interactions. Rice 2014, 7 (1): 20.
24．Yang, F.; Tian, F.; Li, X.;Fan, S.; Chen, H.; Wu, M.; Yang, C. H.; He, C.*, The degenerateEAL-GGDEF domain protein Filp functions as a cyclic di-GMP receptor andspecifically interacts with the PilZ-domain protein PXO_02715 to regulatevirulence in Xanthomonas oryzae pv. oryzae. Mol Plant Microbe Interact2014, 27 (6): 578-89.
25．Li, X.*; Qiao, J.; Yang,L.; Li, X.; Qiao, S.; Pang, X.; Tian, F.; Chen, H.; He, C., Mutation ofalkyl hydroperoxide reductase gene ahpC of Xanthomonas oryzae pv. oryzae affects hydrogen peroxideaccumulation during the rice-pathogen interaction. Res Microbiol 2014,165 (8): 605-11.
26．Yang, F.†; Tian, F.†; Sun, L.†; Chen, H.;Wu, M.; Yang, C. H.; He, C.*, A novel two-component system PdeK/PdeR regulatesc-di-GMP turnover and virulence of Xanthomonas oryzaepv. oryzae. MolPlant Microbe Interact 2012, 25 (10): 1361-9.
27．Chen, H.†; Xue, L.†; Chintamanani,S.†; Germain, H.;Lin, H.; Cui, H.; Cai, R.; Zuo, J.; Tang, X.; Li, X.; Guo, H.; Zhou, J. M.*,ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 repress SALICYLIC ACIDINDUCTION DEFICIENT2 expression to negatively regulate plant innate immunity inArabidopsis. Plant Cell 2009, 21 (8): 2527-40.
28．Chen, H.; Zou, Y.;Shang, Y.; Lin, H.; Wang, Y.; Cai, R.; Tang, X.; Zhou, J. M.*, Fireflyluciferase complementation imaging assay for protein-protein interactions inplants. Plant Physiol 2008, 146 (2): 368-76.
29．胡积祥，朱秀梅，余超，杨凤环，王继春，张立新，陈华民*.miR1320表达水平与水稻白叶枯病抗性的关联性分析。植物保护 2021, 47(5):110-117
30．胡积祥†，曹雅倩†，朱秀梅，余超，田芳，杨凤环，陈华民*，何晨阳。基于瞬时表达系统的水稻miRNA靶基因快速验证系统的建立。生物技术通报 2019, 35(10):57-63.
31．陈禹彤，陈华民*，余超，Amy Thein，田芳，何晨阳。水稻miR169o及其靶基因OsNF-YAs对缺水胁迫的早期表达反应。生物技术通报 2015, 31(8): 76-81.
32．刘维振†，陈华民†，于清，田芳，唐嘉义，何晨阳。鞭毛素蛋白FliCxcv对水稻免疫反应的诱导功能鉴定。植物病理学报 2015, 45(2): 151-157.
33．刘莹，陈华民，于清，田芳，鲁国东，何晨阳。鞭毛素蛋白诱导水稻免疫反应的活性测定。植物保护学报 2015, 42(1):66-71.
34．伍甜，刘莹，余超，边强，田芳，黄琼，陈华民*，何晨阳。燕麦嗜酸菌鞭毛素的提纯及其活性检测。生物技术通报 2013, (7): 78-81
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