团队现有在岗职工19人，其中骨干15人、助理4人；现有研究员5人、副研究员4人、助理研究员10人，拥有博士的学位15人、硕士学位4人，另有博士后3人、硕博士研究生和科研助理80余人；人才方面，有万人计划领军人才1人、创新人才推进计划”中青年科技创新领军人才1人、农科英才B类人选1人，院青年英才培育工程人选2人、农村农业部售药评审专家1人，甘肃省杰青获得者3人。

主持国家重点研发计划课题、国际合作项目、国家自然科学基金面上项目、甘肃省杰出青年基金等项目课题累计8项。累计到账资金600余万元。

1.农业农村部“杰出青年农业科学家”（2018）

2.甘肃省领军人才 （2019）

3.甘肃省杰青 （2016）

4. 中国农业科学院“青年英才” （2019）

5. 中国农学会“青年科技奖”（2020）

6. 甘肃省工业新产品一等奖（2019）

7.中国农业科学院杰出科技创新奖（2021）

发表文章列表（以第一或通讯作者发表SCI论文发30余篇，其中Journal of Virology 6篇（1篇入选封面文章，1篇入选亮点文章），Journal of Immunology 3篇（1篇入选封面文章））：

(1)      Shuying Chen, Fan Yang, Weijun Cao, HuishengLiu, Bo Wen, Yuefeng Sun, Haixue Zheng, Jingyu Wang*, Zixiang Zhu*.Quantitative Proteomics Reveals a Novel Role of the E3Ubiquitin-Protein Ligase FANCL in the Activation of the Innate Immune Responsethrough Regulation of TBK1 Phosphorylation during Peste des Petits RuminantsVirus Infection. J Proteome Res. 2021. 20(8):4113-4130.

(2)      Xiangle Zhang, Fan Yang, Kangli Li, Weijun Cao,Yi Ru, Shuying Chen, Shasha Li, Xiangtao Liu, Zixiang Zhu*, Haixue Zheng*. The Insufficient Activation ofRIG-I-Like Signaling Pathway Contributes to Highly Efficient Replication ofPorcine Picornaviruses in IBRS-2 Cells. Mol Cell Proteomics. 2021. 14; 20:100147

(3)      Huisheng Liu#, Zixiang Zhu#,Tao Feng, Zhao Ma, Qiao Xue, Panxue Wu, Pan Li, Shasha Li, Fan Yang, WeijunCao, Zhaoning Xue, Hongjun Chen, Xiangtao Liu, Haixue Zheng*. African swinefever virus E120R protein inhibits interferon-β production by interacting withIRF3 to block its activation. Journal of Virology, 2021. 95(18):e0082421.并列第一

(4)      Pengfei Li#, Zixiang Zhu#,Weijun Cao, Fan Yang, Xusheng Ma, Hong Tian, Keshan Zhang, Xiangtao Liu, HaixueZheng*. Dysregulation of the RIG-I–like receptor pathway signaling by peste despetits ruminants virus phosphoprotein. The Journal of Immunology. 2021. 206(3),ji2000432. 并列第一

(5)      Kazuki Kato, Sadeem Ahmad, Zixiang Zhu,Janet M Young, Xin Mu, Sehoon Park, Harmit S Malik, Sun Hur. Structuralanalysis of RIG-I-like receptors reveals ancient rules of engagement betweendiverse RNA helicases and TRIM ubiquitin ligases. Molecular Cell. 2021. 81(3):599-613.

(6)      Kangli Li, Congcong Wang, Fan Yang, ZixiangZhu*, Zheng Haixue*. Virus-Host Interactions in Foot-and-Mouth DiseaseVirus Infection. Front Immunol. 2021 Feb 26;12:571509.共同通讯

(7)      Congcong Wang, Huanhuan Feng, Xiangle Zhang,Kangli Li, Fan Yang, Weijun Cao, Huisheng Liu, Lili Gao, Zhaoning Xue, XiangtaoLiu, Zixiang Zhu*, Zheng Haixue*. Porcine Picornavirus 3C ProteaseDegrades PRDX6 to Impair PRDX6-mediated Antiviral Function. Virol Sin. 2021 Mar15:1-10共同通讯

(8)      Shasha Li#, Zixiang Zhu#, Fan Yang,Weijun Cao, Jinping Yang, Caina Ma, Zhenxiang Zhao, Hong Tian, Xiangtao Liu,Junwu Ma, Shaobo Xiao and Haixue Zheng*. Porcine Epidemic Diarrhea VirusMembrane Protein Interacted with IRF7 to Inhibit Type I IFN Production duringViral Infection. The Journal of Immunology. 2021. ji2001186

(9)      Zixiang Zhu, Weiwei Li, Xiangle Zhang,Congcong Wang, Lili Gao, Fan Yang, Weijun Cao, Kangli Li, Hong Tian, XiangtaoLiu, Keshan Zhang, Haixue Zheng*. Foot-and-mouth disease virus capsid proteinVP1 interacts with host ribosomal protein SA to maintain the activation ofMAPKs signal pathway and promote virus replication.Journal of Virology, 2020. 94.3: 01350-19.

(10)   Xiangle Zhang#, Zixiang Zhu#,Congcong Wang, Fan Yang, Weijun Cao, Pengfei Li, Xiaoli Du, Furong Zhao,Xiangtao Liu, Haixue Zheng*. Foot-and-Mouth Disease Virus 3B Protein Interactswith Pattern Recognition Receptor RIG-I to Block RIG-I–Mediated ImmuneSignaling and Inhibit Host Antiviral Response. The Journal of Immunology, 2020.205(8), 2207-2221. #并列一作

(11)   Zixiang Zhu, Fan Yang, Weijun Cao,Huanan Liu, Keshan Zhang, Hong Tian, Wen Dang, Jijun He, Jianhong Guo, XiangtaoLiu, Haixue Zheng*. The pseudoknots region of the 5′ untranslated region is adeterminant of viral tropism and virulence of foot-and-mouth disease virus. JVirol, 2019, 02039-18.

(12)   Zixiang Zhu, Pengfei Li, Fan Yang,Weijun Cao, Xiangle Zhang, Wen Dang, Xusheng Ma, Hong Tian, Keshan Zhang,Miaotao Zhang, Qinghong Xue, Xiangtao Liu, Haixue Zheng*. Pestedes petits ruminants virus nucleocapsid protein inhibits beta interferonproduction by interacting with IRF3 to block its activation. J Virol, 2019, 93(16):e00362-19.

(13)   Fan Yang#, Zixiang Zhu#, Weijun Cao, Huanan Liu, Ting Wei, MinZheng, Keshan Zhang, Ye Jin, Jijun He, Jianhong Guo, Xiangtao Liu, HaixueZheng*. Genetic Determinants of Altered Virulence ofType O Foot-and-Mouth Disease Virus. Journal of Virology. 2019. 94(7):e01657-19. #并列一作(入选亮点文章)

(14)   Huisheng Liu, Zixiang Zhu#,Qiao Xue, Fan Yang, Weijun Cao, Keshan Zhang, Xiangtao Liu, Haixue Zheng*.Foot-and-mouth disease virus antagonizes NOD2-mediated antiviral effects byinhibition of NOD2 protein expression. J Virol, 2019, 00124-19. #并列一作

(15)   Zixiang Zhu, Jijun He, Fan Yang, HaixueZheng*, Xiangtao Liu*. "Response to comment on" First detection offoot-and-mouth disease virus O/ME-SA/Ind2001 in China. Transbound Emerg Dis.2019, 66(2):1095-1096.

(16)   Zixiang Zhu, Chuntian Li, Xiaoli Du,Guoqing Wang, Weijun Cao, Fan Yang, Huanhuan Feng, XiangleZhang, Zhengwang Shi, Huanan Liu, Hong Tian, Dan Li, Keshan Zhang, Xiangtao Liu,Haixue Zheng*. Foot-and-mouth disease virus infection inhibits LGP2 proteinexpression to exaggerate inflammatory response and promote viral replication.Cell Death Dis, 2017. 8(4): p. e2747.

(17)   Liu Huisheng，QiaoXue, Weijun Cao, Fan Yang, Linna Ma, Wenjie Liu, Keshan Zhang, Xiangtao Liu, Zixiang Zhu*, Haixue Zheng*. Foot-and-mouthdisease virus nonstructural protein 2B interacts with cyclophilin A, modulatingvirus replication. FASEB J. 2018, 32(12): 6706-6723. *通讯作者

(18)   Zixiang Zhu, Guoqing Wang, Fan Yang,Weijun Cao, Ruoqing Mao, Xiaoli Du, Xiangle Zhang, Chuntian Li, Dan Li, KeshanZhang, Hongbing Shu, Xiangtao Liu, Haixue Zheng*. Foot-and-Mouth Disease VirusViroporin 2B Antagonizes RIG-I-Mediated Antiviral Effects by Inhibition of ItsProtein Expression. J Virol, 2016, 90(24): 11106~11121. *通讯作者

(19)   Zixiang Zhu, Fan Yang, Keshan Zhang, WeijunCao, Ye Jin, Guoqing Wang, Ruoqing Mao, Dan Li, Jianhong Guo, Xiangtao Liu, HaixueZheng*. Comparative Proteomic Analysis of Wild-Type and SAP Domain MutantFoot-and-Mouth Disease Virus-Infected Porcine Cells Identifies theUbiquitin-Activating Enzyme UBE1 Required for Virus Replication，J Proteome Res，2015.10.01，14（10）：4194~4206. * 通讯作者

(20)   Zixiang Zhu, Fan Yang, Pan Chen, Huanan Liu, Weijun Cao, Keshan Zhang,Xiangtao Liu, Haixue Zheng*. Emergence of novel Seneca Valley virusstrains in China, 2017. Transbound Emerg Dis. 2017. 64(4): 1024–1029. * 通讯作者

(21)   Xiangle Zhang, Max Paget, Congcong Wang, ZixiangZhu*, Haixue Zheng*. Innate immune evasion by picornaviruses. EuropeanJournal of Immunology. 2020. 50(9):1268-1282.* 通讯作者

(22)   Pengfei Li, Zixiang Zhu#,Xiangle Zhang, Wen Dang, Linlin Li, Xiaoli Du, Miaotao Zhang, Chunyan Wu, QinghongXue, Xiangtao Liu, Haixue Zheng*, Yuchen Nan*. The Nucleoprotein andPhosphoprotein of Peste des Petits Ruminants Virus Inhibit InterferonsSignaling by Blocking the JAK-STAT Pathway. Viruses. 2019, 11(7): 629. #并列一作

(23)   Feng huanhuan, Zixiang Zhu#, WeijunCao, Fan Yang, Xiangle Zhang, Xiaoli Du, Keshan Zhang, Xiangtao Liu, HaixueZheng*. Foot-and-mouth disease virus induces lysosomal degradation of NME1 toimpair p53-regulated interferon-inducible antiviral genes expression. Celldeath & disease, 2018, 9(9): 885. #并列一作

(24) Li Chuntian, Zixiang Zhu*, Xiaoli Du,Weijun Cao, FanYang, Xiangle Zhang, Huanhuan Feng, Dan Li, Keshan Zhang,Xiangtao Liu, Haixue Zheng*.Foot-and-mouth disease virus induces lysosomal degradation of host proteinkinase PKR by 3C proteinase to facilitate virus. Virology. 2017, 509: 222-231.* 通讯作者

(25) Zixiang Zhu, et al., Zheng Haixue*. First detection offoot-and-mouth disease virus O/ME-SA/Ind2001 in China. Transbound Emerg Dis. 2018, 65.6: 2027-2031 * 通讯作者

(26)  Yang Fan#, Zixiang Zhu#,et al., Zheng Haixue*.Immunogenicity and protective efficacy of an inactivated cell culture-derivedSeneca Valley virus vaccine in pigs. Vaccine. 2018. 36(6):841-846. #共同第一作者，*通讯作者.

(27) Zixiang Zhu，et al.,Zheng Haixue*，Genetic Characterization of aNovel Mutant of Peste Des Petits Ruminants Virus Isolated from Capra ibex inChina during 2015.，BiomedRes Int，2016.01.01，2016：7632769~7632769. * 通讯作者

(28) Li Weiwei, Zixiang Zhu*, et al., ZhengHaixue*. Esterase D enhances type I interferon signal transduction to suppressfoot-and-mouth disease virus replication.，MolImmunol，2016.7.01，75：112~121. * 通讯作者

(29) Li Pengfei，et al. ,Zixiang Zhu*, Zheng Haixue*. RIG-I is responsible for activation of typeI interferon pathway in Seneca Valley virus-infected porcine cells to suppressviral replication. Virol J, 2018, 15(1): 162. *通讯作者

(30) Shasha Li,,Jinping Yang, Zixiang Zhu*,Haixue Zheng*. Porcine Epidemic Diarrhea Virus and the Host Innate ImmuneResponse. Pathogens. 2020. 9(5):367. *通讯作者

(31) Chen Pan，et al. ,Zixiang Zhu*, Zheng Haixue*. The Distribution of Different Clades ofSeneca Valley Viruses in Guangdong Province, China. Virologica Sinica. 2018,33(5): 394-401.

(32) Zixiang Zhu, et al., Zheng Haixue*. EarlyGrowth Response Gene-1 Suppresses Foot-and-Mouth Disease Virus Replication byEnhancing Type I Interferon Pathway Signal Transduction. Frontiers inmicrobiology, 2018, 9: 2326.

(33) Liu Yingqi#, Zixiang Zhu#, et al. ZhengHaixue*. Multifunctional roles of leader protein of foot-and-mouth diseaseviruses in suppressing host antiviral responses，VeterinaryResearch，2015 , 46 (1) :127. #共同第一作者，*通讯作者

(34) Ni Zixin，et al.,Zixiang Zhu*，Zheng Haixue*. Differentialgene expression in porcine SK6 cells infected with wild-type and SAPdomain-mutant foot-and-mouth disease virus.，VirolSin，2016.6.01，31（3）：249~257. *通讯作者

参编论著

（1）《口蹄疫》，著作，中国农业出版社，参编，2015年出版；

（2）《兽医传染病实验指导》，教材，中国农业大学出版社，副主编，2017年出版。