国家自然科学基金委员会，面上项目，31872468，牛支原体引起宿主细胞凋亡及持续性感染的分子机制，2019-01至2022-12，61万元，在研，参加

国家自然科学基金委员会，青年基金项目，31402249，AI-2/LuxS介导的QS系统调控禽肠炎沙门氏菌耐药性与致病力的研究，2015-01至2017-12，25万元，已结题，主持

国家自然科学基金委员会，青年基金项目，31400119，控制致病性大肠杆菌DegP表达的调控蛋白及其调控机制研究，2015-01至2017-12, 24万元，已结题，参加

国家自然科学基金委员会，青年基金项目，31201862，奶牛源耐甲氧西林金黄色葡萄球菌流行特点及甲氧西林耐药新机制研究，2013-01至2015-12，23万元，已结题，参加

中央级公益性科研院所基本科研业务费专项，0302013014，blaNDM-1基因引起大肠杆菌耐药与适应性代价研究，2013-01至2014-12，20万，已结题，主持

(1). Pan Qiao, Wang Xiumei, Liu Tong, Yu Ying, Li Lu, Zhou Rui, Li Ganwu, Xin Jiuqing. Mycoplasma hyopneumoniae Inhibits Porcine Beta-Defensin 2 Production by Blocking the Unfolded Protein Response To Facilitate Epithelial Adhesion and Infection. Infect Immun. 2020,88(7):e00164-20.

(2). Xiumei Wang, Yao Zhu, Xin Hua, Fuguang Chen, Changzhen Wang, Yanhe Zhang, Siguo Liu,Wanjiang Zhang*..F14:A-:B- and IncX4 Inc group cfr-positive plasmids circulating (3)In Escherichia coli of animal origin in Northeast China. 2018, 217:53-57.

 (3). Xiu-Mei Wang, Zhimin Dong, Stefan Schwarz, Yao Zhu, Xin Hua,Yanhe Zhang,Siguo Liu,Wan-Jiang Zhang*. Plasmids of Diverse Inc Groups Disseminate the Fosfomycin Resistance Gene fosA3 among Escherichia coli Isolates from Pigs, Chickens, and Dairy Cows in Northeast China. Antimicrobial Agents and Chemotherapy, 2017,59(2):7113-7116.

 (4). Wan-Jiang Zhang, Xiu-Mei Wang, Lei Dai, Xin Hua, Zhimin Dong, Stefan Schwarz, Siguo Liu*. Novel conjugative plasmid from Escherichia coli of swine origin that coharbors the multiresistance gene cfr and the extended-spectrum-β-lactamase gene blaCTX-M-14b. Antimicrobial Agents and Chemotherapy, 2015,59(2):1337-1340. (first co-authors)

(5). Xiu-Mei Wang, Xing-Feng Lü, Lu Yin, Hui-Fang Liu, Wan-Jiang Zhang, Wei Si, Shen-Ye Yu , Mei-Li Shao, Si-Guo Liu*. Occurrence and antimicrobial susceptibility of Listeria monocytogenes isolates from retail raw foods. Food Control, 2013,32 (1):153-158.

(6). Xiu-Mei Wang, Wan-Jiang Zhang, Stefan Schwarz, Shen-ye Yu, Huifang Liu, Wei Si, Rong-Min Zhang, and Siguo Liu*. Methicillin-resistant Staphylococcus aureus ST9 from a case of bovine mastitis carries the genes cfr and erm(A) on a small plasmid. Journal of Antimicrobial Chemotherapy, 2012, 67(5):1287-1289.

(7). Bao-Tao Liu, Xiu-Mei Wang, Xiao-Ping Liao, Jian Sun, Heng-Qian Zhu, Xue-Ying Chen and Ya-Hong Liu*. Plasmid-mediated quinolone resistance determinants oqxAB, aac(6`)-Ib-cr and extended-spectrum β-lactamase gene blaCTX-M-24 colocated on the same plasmid in one Escherichia coli strain from China. Journal of Antimicrobial Chemotherapy, 2011, 66 (7): 1638- 1639. (first co-authors)

(8). Xiu-Mei Wang, Xiao-Ping Liao, Si-Guo Liu, Wan-Jiang Zhang, Hong-Xia Jiang, Mei-Jun Zhang, Heng-Qian Zhu, Ying Sun, Jian Sun, Ai-Xin Li, Ya-Hong Liu*. Serotypes, virulence genes and antimicrobial susceptibility of Escherichia coli isolates from pigs. FEMS Microbiology Letters, 2010,306: 15-21.

(9). Xiu-Mei Wang, Xiao-Ping Liao, Wan-Jiang Zhang, Hong-Xia Jiang, Jian Sun, Mei-Jun Zhang,Xue-Fang He, Dong-Xing Lao, and Ya-Hong Liu*. Prevalence of Serogroups, Virulence Genotypes, Antimicrobial Resistance, and Phylogenetic Background of Avian Pathogenic Escherichia coli in South of China. Foodborne Pathogens Disease, 2010,7(9):1099-1106.

(10). Wei Si, Xiumei Wang, Huifang Liu, Shenye Yu, Zhaoli Li, Liping Chen, Wanjiang Zhang, Siguo Liu*. Physiology, pathogenicity and immunogenicity of live, attenuated Salmonella enterica serovar Enteritidis mutants in chicks. Microbial Pathogenesis, 2015,(83-84):6-11.

(11). Huifang Liu, Liping Chen, XiumeiWang,Wei Si, HuananWang, ChunlaiWang,Siguo Liu*, Guangxing Li*.Decrease of colonization in the chicks' cecum and internal organs of Salmonella enterica serovar Pullorum by deletion of cpdB by Red system. Microbial Pathogenesis,2015, 80:21-26.

(12). Hongbin Si, Wan-Jiang Zhang, Shengbo Chu, Xiu-Mei Wang, Lei Dai, Xin Hua,Zhimin Dong, Stefan Schwarz, Siguo Liu*. Novel Plasmid-Borne Multidrug Resistance Gene Cluster Including lsa(E) from a Linezolid-Resistant Enterococcus faecium Isolate of Swine Origin. Antimicrobial Agents and Chemotherapy, 2015, 59: 7113-7116.