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中国农业科学院兰州畜牧与兽药研究所兽药创新与耐药性团队青年助理首席,主要从事基于西部药用植物资源的抗动物寄生虫先导化合物的发现、作用机理研究,及药材非药用部位(部分)的综合利用研究。近年来,先后主持国家自然科学基金面上项目、青年基金等多个项目,以第一完成人获甘肃省自然科学三等奖1项、甘肃省情报学会情报科技进步三等奖1项,参与获得省部级科研奖励3项、新兽药证书3个;发表论文60余篇,其中以第一作者或通讯(含共同)发表SCI论文32篇,总影响因子近180,影响因子大于10的4篇,2篇为ESI高被引论文;出版著作3部,其中主编1部,参编2部;以第一发明人获国家发明专利10项,软件著作权2项,建立中、英、藏文版《中国藏兽医药数据库系统》(http://zsyy.lzmy.org.cn/);被聘为藏药新药开发国家重点实验室资源研究基地客座教授、Frontiers in Veterinary Sciences和BMC Veterinary Reseach杂志Associate Editor和编委,中国化学会农业化学委员会青工委,国际传统药理学会(ISE)青年工作成员。
主持项目:
1. 国家自然科学基金面上项目“基于双靶点的藏药蓝花侧金盏杀螨活性成分分离、结构优化及构效关系研究”,60 万元,2018年01月至 2021年12月;
2. 国家自然科学基金青年基金“藏药蓝花侧金盏有效部位杀螨作用机理研究”,23万元,201年01月至2016年12 月;
3. 甘肃省青年科技基金“丁香酚杀螨作用机理研究及衍生物的合成与优化”,2 万元,2015年07月至 2017年06月;
4. 青海省青年科技基金“藏药雪山杜鹃的抗氧化活性成分及其作用机理研究”子课题,3万元,2018年01月至 2020年12月;
5. 中国农业科学院院统筹基本科研业务费项目“基于多组学和SPR技术的 藏药抗寄生虫活性成分与作用机理研究”,50万元,2019年01月至2020年12月。
参与国家科技支撑计划、科技基础专项、公益性行业专项、甘肃省科技支撑计划等多个项目。
7. Biologically active isoquinpoline alkaloids covering 2014-2018. Medicinal Research Reviews. 2020, 40(6): 2212-2289.
8. The active compounds and AChE inhibitor of the methanol extract of Adonis coerulea maxim against Psoroptes cuniculi, Veterinary Parasitology, 2020, 186, 109247
9. The acaricidal mechanism and active compounds against Psoroptes cuniculi of the methanol extract of Adonis coerulea Maxim II: Integrated proteomics and SPR analysis, Veterinary Parasitology, 2020, 187, 109267
10. Insecticidal and antifungal activities of Rheum palmatum L. anthraquinones and structurally related compounds. Industrial Crops & Products, 2019, 137, 508-520.
11. Acaricidal activity and enzyme inhibitory activity of active compounds of essential oils against Psoroptes cuniculi. Veterinary Parasitology, 2019, 267, 54-59.
12. The Genus Adonis as an Important Cardiac Folk Medicine: A Review of the Ethnobotany, Phytochemistry and Pharmacology. Frontier in Pharmacology 2019, 10:25. doi: 10.3389/fphar.2019.00025.
13. The anti-diarrheal activity of the nontoxic Dihuang powder in mice. Frontier in Pharmacology 2018, DOI: 10.3389/fphar. 2018.01037.
14. Biologically active quinoline and quinazoline alkaloids part II. Medicinal Research Review, 2018;1–47.
15. Application of sustainable natural resources in agriculture: acaricidal and enzyme inhibitory activities of naphthoquinones and their analogs against Psoroptes cuniculi. Scientific Reports, 2018, 8:1609
16. Biologically active quinoline and quinazoline alkaloids part I. Medicinal Research Review, 2017;1–54.
17. The toxicity and the acaricidal mechanism against Psoroptes cuniculi of the methanol extract of Adonis coerulea Maxim. Veterinary Parasitology, 2017, 240, 17–23.
18. Gymnadenia conopsea (L.) R.Br.: A Systemic Review of the Ethnobotany, Phytochemistry, and Pharmacology of an Important Asian Folk Medicine. Front. Pharmacol. 2017, 8:24. doi: 10.3389/fphar.2017.00024.
19. Ultrasound-assisted extraction of polysaccharides from Rhododendron aganniphum: Antioxidant activity and rheological properties. Ultrasonics Sonochemistry, 2017, 38, 246–255.
20. Acaricidal activities of the essential oil from Rhododendron nivale Hook. f. and its main compound, δ-cadinene against Psoroptes cuniculi. Veterinary Parasitology 2017, 236, 51–54.
著作
1. 若尔盖高原常用藏兽药及器械图谱,27.4万字,2015年9月,中国农业科 技出版社,主编;
2. Ethnopharmacology, Phytochemistry and Pharmacology Review of Traditional Chinese Medicicne-1, 80万字, 2015年8月, Science Press, 主要撰稿 人;
3. Xiaofei Shang, Xirui He. Clove oil: Biological activities and usage. J.N. Govil. Recent Progress in Medicinal Plants. Studium Press, LLC. 2012。
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