学习经历：

2003.9-2006.7 西北农林科技大学，博士

2000.9-2003.7 西北农林科技大学，硕士

1996.9-2000.7 山东农业大学，学士

工作经历：

2009.9-至今 中国农业科学院，饲料研究所

2019.1-2020.1 昆士兰大学，访问学者

2006.9-2009.8 北京林业大学，博士后

研究内容：

1）活性小分子对大肠杆菌、肠炎沙门氏菌等G‒病原菌杀菌机理的研究，应用细胞学、分子生物学及组学等技术分别从细胞、基因和蛋白水平研究生物活性分子诱导畜禽腹泻致病菌G−类细胞凋亡及其类凋亡机制；

2）活性小分子定点定向设计、分子改造、合成及其修饰，建立与内毒素结合域的关键序列，并建立内毒素血症、病原菌肠炎模型。

3）防人对宠物过敏制剂的创制，研究特异性阻隔分子设计、制备及其功效。

获奖情况：

2020年，颐和青年创新奖

2019年，中华农业科技一等奖（第4完成人）

2017年，北京市科学技术奖一等奖（第5完成人）

2014年，北京市科学技术奖三等奖（第3完成人）

2013年，第八届大北农科技奖（第2完成人）

学术兼职：

Front Cell Infect Microbiol,Guest Associate Editor (2021-)

Antibiotics, Topical Editor(2021-)

Marine Drugs, Editor (2021-)

培养学生：

北京市优秀毕业生1名、中国农业科学院优秀毕业生2名、中国农业科学院优秀硕士学位论文1名。

代表性研究论文（一作/通讯作者）：

1)     Wang JX, Tao H, Fan QY,Wang ZL, Han B, Wang XM, Wang JQ. Anti-bacterial and anti-inflammatory propertiesof sophoridine and its effect on diarrhea in mice. Int J Mol Sci,2025, 26:2122. (IF4.9)

2)     Wang JX, An W, Wang ZL,Zhao Y, Han B, Tao H, Wang JQ, Wang XM. Vanillin has potent antibacterial, antioxidant,and anti-Inflammatory activities in vitro and in mouse colitis induced by multidrug-resistantEscherichia coli. Antioxidants, 2024,13:1544. (IF6.6)

3)     Bojarska J, Wang XM, SkwarczynskiM. Editorial: Peptides against infectious diseases: from antimicrobial peptidesto vaccines. Front Pharmacol, 2024. (IF4.8)

4)     An W, Li T, Tian XY, FuXX, Li CX, Wang ZL, Wang JQ, Wang XM. Allergies toallergens from cats and dogs: A review and update on sources, pathogenesis, andstrategies. Int J Mol Sci, 2024, 25:10520. (IF4.9)

5)      Li CX, Li T, Tian XY, An W, Wang ZL, Han B, Tao H, Wang JQ, Wang XM. Research progress on thePEGylation of therapeutic proteins and peptides (TPPs). Front Pharmacol, 2024, 15:1353626. (IF4.8)

6)     Wang ZL, Teng D, Ma RY,Hao Y, Yang N, Wang XM, Wang JH. A cleavable chimeric peptide with targetingand killing domains enhances LPS neutralization and antibacterial propertiesagainst multi-drug resistant E. coli. Commun Biol,2023, 6(1):1170. (IF5.1)

7)      Li T, Wang ZL, Guo JH, dela Fuente-Nunez C, Wang JQ, Han B, Tao H, Liu J, Wang XM. Bacterial resistance to antibacterial agents: mechanisms,control strategies, and implications for global health. Sci Total Env, 2023, 860:160461.(IF8.0)

8)     Xu CM, Kong LQ, Gao HF,Cheng XY, Wang XM. A review of currentbacterial resistance to antibiotics in food animals. Front Microbiol,2022, 13:822689. (IF4.5)

9)      Han HH, Teng D, Mao RY, Hao Y, Yang N, WangZL, Li T, Wang XM, Wang JH. Marine peptide-N6NH2 and its derivative-GUON6NH2have potent antimicrobial activity against intracellular Edwardsiella tarda in vitro and invivo. Front Microbiol, 2021,12: 637427. (IF4.5)

10)    Li T, Wang ZL, Han HH, Teng D, Mao RY, Hao Y,Yang N, Wang XM, Wang JH. Dual antibacterial activities and biofilm eradicationof a marine peptide-N6NH2 and its analogs against multidrug-resistant Aeromonas veronii.Int J Mol Sci, 2020, 21: 9637. (IF4.9)

11)    Li T, Teng D, Mao RY, Hao Y, Wang XM, Wang JH.A critical review of antibiotic resistance in probiotic bacteria. Food Res Int,2020, 36:109571. (IF8.0)

12)    Wang ZL, Liu XH, Teng D, Mao RY, Hao Y, YangN, Wang X, Li ZZ, Wang XM, Wang JH. Development of chimeric peptides tofacilitate the neutralisation of lipopolysaccharides during bactericidaltargeting of multidrug-resistant Escherichiacoli. Commu Bio, 2020,3(1), 41. (IF5.1)

13)    Han HH, Li T, Wang ZL, Teng D, Mao RY, Hao Y,Yang N, Wang XM, Wang JH. Improved stability and activity of a marinepeptide-N6NH2against Edwardsiellatarda and its preliminary application in fish. Mar Drugs, 2020, 18:650. (IF5.4)

14)    Han HH, Wang ZL, Li T, Teng D, Mao RY, Hao Y,Yang N, Wang XM, Wang JH. Recent progress of bacterial FtsZ inhibitors with afocus on peptides. J FEBS, 2020, 288 (4): 1091-1106. (IF4.2)

15)    Li ZZ, Teng D, Mao RY, HaoY, Wang X, Wang XM,Wang JH. Improved antibacterial activity of themarine peptide N6 againstintracellular Salmonella Typhimuriumby conjugating with the cell-penetrating peptide Tat11 via a cleavable linker. J Med Chem, 2018, 61(17):7991-8000. (IF6.8)

16)    Li ZZ, Mao RY, Teng D, HaoY, Chen HX, Wang XM,Wang JH. Improved antibacterial activity of a marine peptide-N2 againstintracellular Salmonellatyphimurium byconjugating with cell-penetratingpeptides-bLFcin6/Tat11. Eur J Med Chem, 2017,145:263. (IF5.9)

17)    Wang XM, Teng D, Mao RY, Yang N, Hao Y, WangJH. Combined systems approaches reveal a multistage mode of action of a marineantimicrobial peptide against pathogenic Escherichia coli and its protectiveeffect against bacterial peritonitis and endotoxemia. Antimicrob AgentsChemother, 2016, 61(1):e01056-16. (IF5.3)

18)    Wang XM, Teng D, Guan QF, Tian F, Wang JH.Detection of genetically modified crops using multiplex asymmetric polymerasechain reaction and asymmetric hyperbranched rolling circle amplification coupled with reverse dot blot. FoodChem, 2015, 173: 1022-1029. (IF9.8)

19)    Wang XM, Teng D, Guan QF, Tian F, Wang JH.Detection of Roundup Ready soybean by loop-mediated isothermal amplificationcombined with a lateral-flow dipstick. Food Control, 2013, 29: 213-220. (IF6.3)

20)    Wang XM, Teng D, Guan QF, Tian F, Wang JH.Comparison of three DNA extraction methods for feed products and fouramplification methods for the 5´-junction fragment of Roundup Ready soybean. JAgri Food Chem, 2012,60(18):4586-4595. (IF6.1)